ReviewFrontiers of medicine2013
Primary hypertrophic osteoarthropathy: an update.
Review in Frontiers of medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 71 citations in OpenAlex.
- Acquired digital clubbing in 2 healthy young men: The incomplete form of pachydermoperiostosis (primary hypertrophic osteoarthropathy).JAAD case reports · 2026Article
- Bone Density, Microarchitecture, and Geometry Assessment in Patients with Pachydermoperiostosis Using Second-Generation High-Resolution Peripheral Quantitative Computed Tomography: A Case-Control Study.Calcified tissue international · 2025Article
- Targeting Metabolomics in Primary Hypertrophic Osteoarthropathy: Uncovering Novel Insights into Disease Pathogenesis.The Journal of clinical endocrinology and metabolism · 2025Article
- Distinct features of three clinical subtypes in 533 patients with primary hypertrophic osteoarthropathy.Orphanet journal of rare diseases · 2025Article
- Paraneoplastic Dermatoses: A Clue for Underlying Malignancies.Journal of clinical medicine · 2025Review
- Band Acro-Osteolysis as a Less Common Radiologic Pattern in Systemic Scleroderma: A Case Report.Clinical medicine insights. Case reports · 2025Article
- Inflammatory Granulomas, Accompanied by Mild Proliferation of Spinous Layer in Primary Hypertrophic Osteoarthropathy.Indian journal of pediatrics · 2024Article
- Case report: Novel homozygous HPGD variant leads to primary hypertrophic osteoarthropathy with intussusception and acro-osteolysis in a Chinese family.Frontiers in pediatrics · 2023Article
- Primary hypertrophic osteoarthropathy: genetics, clinical features and management.Frontiers in endocrinology · 2023Review
- Clinical and biochemical characteristics of 12 Chinese primary hypertrophic osteoarthropathy patients with HPGD mutations.International journal of biological sciences · 2022Article
- Etoricoxib as a treatment of choice for patients withFrontiers in genetics · 2022Article
- Clinicopathologic Conference: A Four-Year-Old Child With Digital Clubbing.Arthritis care & research · 2021Article
- Lost bones: differential diagnosis of acro-osteolysis seen by the pediatric rheumatologist.Pediatric rheumatology online journal · 2021Review
- Herbst's Triad as a Manifestation of Gastroesophageal Reflux Disease.JPGN reports · 2021Article
- Article
- Frontal lifting using a tissue expander in pachydermoperiostosis: A case report.Clinical case reports · 2021Article
- Incomplete primary hypertrophic osteoarthropathy.BMJ case reports · 2020Article
- Characteristic Facial Appearance Was the Key to Diagnosing Chronic Enteropathy Associated withInternal medicine (Tokyo, Japan) · 2020Article
- Article
- Impaired bone microarchitecture in distal interphalangeal joints in patients with primary hypertrophic osteoarthropathy assessed by high-resolution peripheral quantitative computed tomography.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Digital clubbing, which has been recognized as a sign of systemic disease, is one of the most ancient diseases. However, the pathogenesis of clubbing and hypertrophic osteoarthropathy has hitherto been poorly understood. The study of a clinically indistinguishable idiopathic form (primary hypertrophic osteoarthropathy, PHO) provides an opportunity to understand the pathogenesis of hypertrophic osteoarthropathy. Current advances in the study of PHO are discussed. The impaired metabolism of prostaglandin E2 (PGE2) plays a central role in its pathogenesis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.