ArticleHernia : the journal of hernias and abdominal wall surgery2013
Comparative study of shrinkage, inflammatory response and fibroplasia in heavyweight and lightweight meshes.
Article in Hernia : the journal of hernias and abdominal wall surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- International guidelines for groin hernia management.Hernia : the journal of hernias and abdominal wall surgery · 2018Guideline
- PVDF versus polypropylene large pore mesh for open incisional hernia repair - a case control matched analysis.Hernia : the journal of hernias and abdominal wall surgery · 2026Article
- Killing two birds with one stone: A therapeutic copper-loaded bio-patch promoted abdominal wall repair via VEGF pathway.Materials today. Bio · 2023Article
- An easier Lichtenstein hernioplasty.Hernia : the journal of hernias and abdominal wall surgery · 2018Article
- Case series of recurrent inguinal hernia after primary TREPP repair: re-TREPP seems feasible and safe.International journal of surgery case reports · 2018Article
- Comparison of partially-absorbable lightweight mesh with heavyweight mesh for inguinal hernia repair: multicenter randomized study.Annals of surgical treatment and research · 2017Article
- Polypropelene-mesh properties and type of anchoring do not influence strength of parietal ingrowth.Langenbeck's archives of surgery · 2017Article
- Nitric oxide coating polypropylene mesh increases angiogenesis and reduces inflammatory response and apoptosis.International urology and nephrology · 2017Article
- Mesh shrinkage depends on mesh properties and anchoring device: an experimental long-term study in sheep.Hernia : the journal of hernias and abdominal wall surgery · 2017Article
- Experimental study of inflammatory response and collagen morphometry with different types of meshes.Hernia : the journal of hernias and abdominal wall surgery · 2016Article
- Surgical mesh for ventral incisional hernia repairs: Understanding mesh design.Plastic surgery (Oakville, Ont.) · 2016Review
- Mesh implants: An overview of crucial mesh parameters.World journal of gastrointestinal surgery · 2015Article
- Long-term evaluation of adhesion formation and foreign body response to three new meshes.Surgical endoscopy · 2015Article
- Evaluation of three purely polypropylene meshes of different pore sizes in an onlay position in a New Zealand white rabbit model.Hernia : the journal of hernias and abdominal wall surgery · 2014Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIn this manuscript, the authors describe an animal study comparing shrinkage, inflammatory response and fibroplasia in heavyweight (HW-PP) and lightweight polypropylene (LW-PP) meshes.
methodsBoth meshes were fixed on abdominal fascia of 25 Wistar rats (epifascial onlay placement). They were killed at 7, 28 and 90 days to measure the prostheses. Histological analysis was performed with hematoxylin-eosin for cellular counting and immunohistochemistry to measure collagen types I and III.
resultsThe authors found that the LW-PP mesh presented greater median shrinkage than HW-PP mesh at 7 (P = .036), 28 (P = .674) and 90 days (P = .038) postoperatively. There were more neutrophils on LW-PP mesh (P = .008) at 7 days, gradually diminishing in both prostheses. Lymphocytes were similar between the implants at 7 days, diminishing about 50 % on LW-PP mesh (P < .001) at 90 days. Macrophages and giant cells diminished on LW-PP and increased on HW-PP meshes (P < .001). Collagen I/III ratio presented a progressive, almost fivefold rise at 90 days, on both mesh types (P < .001). The collagen I/III ratio was similar between LW-PP and HW-PP meshes at the three times studied.
conclusionsIt is concluded that LW-PP showed more shrinkage than HW-PP mesh at 7 and 90 days, despite the fact that HW-PP presented more lately foreign body reaction. The collagen I/III ratio was similar between the prostheses and increased during the postimplant period.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.