Evidence map›Paper›PMID 23344664›Full record

ArticleClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2013

Nanoemulsions and nanoparticles for non-melanoma skin cancer: effects of lipid materials.

P Severino, J F Fangueiro, S V Ferreira, R Basso, M V Chaud, M H A Santana, A Rosmaninho, E B Souto

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 47 citations in OpenAlex.

  1. Review
  2. Nanoparticles as a Therapeutic Delivery System for Skin Cancer Prevention and Treatment.JID innovations : skin science from molecules to population health · 2023
    Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
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  10. Article
  11. New Nanotechnologies for the Treatment and Repair of Skin Burns Infections.International journal of molecular sciences · 2020
    Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

P SeverinoDepartment of Biotechnological Processes, School of Engineering Chemical, University of Campinas-Unicamp, Campinas, 13083-970, Brazil.
J F Fangueiro
S V Ferreira
R Basso
M V Chaud
M H A Santana
A Rosmaninho
E B Souto
Universidade Estadual de Campinas (UNICAMP) · BRFernando Pessoa University · PTHospital de Santo António · PTUniversidade de Sorocaba · BRUniversity of Trás-os-Montes and Alto Douro · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Basal cell carcinomas and squamous cell carcinomas are non-melanoma skin cancers reported to be among the most common malignancies, being responsible for high human morbidity. Conventional chemotherapy applied to these conditions shows non-specific targeting, thus severe adverse side effects are also commonly reported. New therapeutic strategies based on nanoparticulates technology have emerged as alternatives for site specific chemotherapy. Among the different types of nanoparticulates, lipid nanoemulsions and nanoparticles have several advantages for topical delivery of poorly soluble chemotherapeutics. These particles show sustained drug release and protection of loaded drugs from chemical degradation. This technology is promising to enhance the intracellular concentration of drugs and consequently reduce the cytotoxicity of skin chemotherapy.

Indexed as

Drug CarriersNanoparticlesAntineoplastic AgentsBasal Cell CarcinomaCarcinoma, Squamous CellEmulsionsHumansLipidsSkin NeoplasmsAntineoplastic AgentsDrug CarriersEmulsionsLipids

Identifiers

PMID23344664
OpenAlexW2082563202

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.