ArticleNature chemistry2013
A backbone lever-arm effect enhances polymer mechanochemistry.
Article in Nature chemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed.
- Modeling Targeted Mechanochemistry in Polymeric Solids.Chemical reviews · 2026Review
- Computational Exploration of Polymer Mechanochemistry: Quantitation of Activation Force and Systematic Discovery of Reaction Sites by the Extended Artificial Force-Induced Reaction Method.Journal of the American Chemical Society · 2025Article
- "Node" facilitated thermostable mechanophores for rapid self-strengthening in double network materials.Chemical science · 2025Article
- Force-Accelerated Ring Opening of Episulfide by Pulsed Ultrasonication.Macromolecules · 2025Article
- Polymer microbubbles as universal platform to accelerate polymer mechanochemistry.Nature communications · 2025Article
- Mechanochemistry: Fundamental Principles and Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Structure-property relationships for the force-triggered disrotatory ring-opening of cyclobutene.Chemical science · 2025Article
- Expanding the Molecular Switches Toolbox: Photoreloadable Dithienylethene Mechanophores.Angewandte Chemie (International ed. in English) · 2025Article
- The Role of Torsion on the Force-Coupled Reactivity of a Fluorenyl Naphthopyran Mechanophore.Journal of the American Chemical Society · 2025Article
- Advancing the Mechanosensitivity of Atropisomeric Diarylethene Mechanophores through a Lever-Arm Effect.Journal of the American Chemical Society · 2025Article
- Furan Release via Force-Promoted Retro-[4+2][3+2] Cycloaddition.Journal of the American Chemical Society · 2023Article
- Editing of polymer backbones.Nature reviews. Chemistry · 2023Review
- A rational design strategy of radical-type mechanophores with thermal tolerance.Chemical science · 2023Article
- Competitive Activation Experiments Reveal Significantly Different Mechanochemical Reactivity of Furan-Maleimide and Anthracene-Maleimide Mechanophores.ACS polymers Au · 2023Article
- Off-center Mechanophore Activation in Block Copolymers.Angewandte Chemie (International ed. in English) · 2023Article
- From Inert to Catalytically Active Milling Media: Galvanostatic Coating for Direct Mechanocatalysis.Angewandte Chemie (International ed. in English) · 2022Article
- Critical stresses in mechanochemical reactions.Chemical science · 2022Article
- Angle-dependent strength of a single chemical bond by stereographic force spectroscopy.Chemical science · 2022Article
- Single-Molecule Force Spectroscopy of a Tetraaryl Succinonitrile Mechanophore.The journal of physical chemistry. C, Nanomaterials and interfaces · 2022Article
- Ultrasound-controlled drug release and drug activation for cancer therapy.Exploration (Beijing, China) · 2021Review
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5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mechanical forces along a polymer backbone can be used to bring about remarkable reactivity in embedded mechanically active functional groups, but little attention has been paid to how a given polymer backbone delivers that force to the reactant. Here, single-molecule force spectroscopy was used to directly quantify and compare the forces associated with the ring opening of gem-dibromo and gem-dichlorocyclopropanes affixed along the backbone of cis-polynorbornene and cis-polybutadiene. The critical force for isomerization drops by about one-third in the polynorbornene scaffold relative to polybutadiene. The root of the effect lies in more efficient chemomechanical coupling through the polynorbornene backbone, which acts as a phenomenological lever with greater mechanical advantage than polybutadiene. The experimental results are supported computationally and provide the foundation for a new strategy by which to engineer mechanochemical reactivity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.