Evidence map›Paper›PMID 23344397›Full record

ArticleObstetrics and gynecology2013

Management of uterine bleeding during hematopoietic stem cell transplantation.

Stephanie E Purisch, Dana Shanis, Christa Zerbe, Melissa Merideth, Jennifer Cuellar-Rodriguez, Pamela Stratton

Abstract readCase Reports
In one paragraph

Article in Obstetrics and gynecology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Development of institutional guidelines for menstrual suppression and abnormal uterine bleeding in patients undergoing intensive chemotherapy for hematologic malignancies.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Stephanie E PurischDepartment of Obstetrics and Gynecology, Hospital of University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Dana Shanis
Christa Zerbe
Melissa Merideth
Jennifer Cuellar-Rodriguez
Pamela Stratton
Hospital of the University of Pennsylvania · US

Funding

Safety and Immunogenicity of Gardasil post stem cell transplantationZIAHD008900 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI STRATTON, PAMELA · 2010 to 2016
$1.2M
Intramural NIH HHS ZIA HD008900
6 · The paper itself

Abstract

backgroundHematopoietic stem cell transplant is an effective treatment strategy for a variety of hematologic disorders, but patients are at risk for dysfunctional coagulation and abnormal bleeding. Gynecologists are often consulted before transplant for management of abnormal uterine bleeding, which may be particularly challenging in this context. CASE: A premenopausal woman with MonoMAC (a rare adult-onset immunodeficiency syndrome characterized by monocytopenia and Mycobacterium avium complex infections resulting from mutations in GATA2, a crucial gene in early hematopoiesis) presented with pancytopenia, evolving leukemia, and recent strokes, necessitating anticoagulation. During preparation for hematopoietic stem cell transplant, she experienced prolonged menorrhagia requiring transfusions. Surgical therapy was contraindicated, and medical management was successful only when combined with balloon tamponade.

conclusionBalloon tamponade may be a potentially life-saving adjunct to medical therapy for control of uterine hemorrhage before hematopoietic stem cell transplant.

Indexed as

Uterine Balloon TamponadeAdultAntineoplastic Agents, HormonalContraceptives, Oral, SyntheticEstrogensFemaleGATA2 Transcription FactorHematopoietic Stem Cell TransplantationHumansImmunologic Deficiency SyndromesInduction ChemotherapyLeiomyomaLeuprolideMedroxyprogesteroneMenorrhagiaStrokeAntineoplastic Agents, HormonalContraceptives, Oral, SyntheticEstrogensGATA2 protein, humanGATA2 Transcription FactorLeuprolideMedroxyprogesterone

Identifiers

PMID23344397
PMCPMC3798064
OpenAlexW1920319925

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.