Evidence map›Paper›PMID 23344204›Full record

ArticleMolecules (Basel, Switzerland)2013

Chemical composition and antibacterial activity of essential oils from different parts of Leonurus japonicus Houtt.

Liang Xiong, Cheng Peng, Qin-Mei Zhou, Feng Wan, Xiao-Fang Xie, Li Guo, Xiao-Hong Li, Cheng-Jun He, Ou Dai

Open access · goldAbstract readComparative Study
In one paragraph

Article in Molecules (Basel, Switzerland), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
11.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 82 citations in OpenAlex.

  1. Effect of DifferentMolecules (Basel, Switzerland) · 2025
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  8. Anti-Inflammatory and Antibacterial Potential of Qicao Rukang Powder in Bovine Subclinical Mastitis.Evidence-based complementary and alternative medicine : eCAM · 2021
    Article
  9. Review
  10. Article
  11. The Wound Healing Potential ofEvidence-based complementary and alternative medicine : eCAM · 2019
    Review
  12. Review
  13. Chemical Investigation of a Biologically ActiveJournal of analytical methods in chemistry · 2019
    Article
  14. Article
  15. Article
  16. Article
  17. THE ANTIBACTERIAL EFFECT OFAfrican journal of traditional, complementary, and alternative medicines : AJTCAM · 2017
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Liang XiongState Key Laboratory Breeding Base of Systematic Research, Development and Utilization of Chinese Medicine Resources, Sichuan Province and Ministry of Science and Technology, Chengdu 610075, Sichuan, China. xiling0505@126.com
Cheng Peng
Qin-Mei Zhou
Feng Wan
Xiao-Fang Xie
Li Guo
Xiao-Hong Li
Cheng-Jun He
Ou Dai
Chengdu University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The herb and fruits of Leonurus japonicus Houtt., named "Yimucao" and "Chongweizi", respectively, in Chinese, have been widely used in China as gynecological medicines. The components of the essential oils obtained by hydrodistillation were investigated by GC-MS. The antibacterial activity of the essential oils was determined by micro-dilution assay. The results showed large variations in the chemical composition and antibacterial activity of the oils. The oil of "Yimucao" showed antibacterial activity against various Gram-positive bacteria and consisted mainly of sesquiterpenes and diterpenes, with phytone, phytol, caryophyllene oxide and β-caryophyllene being the most significant constituents, whereas the oil of "Chongweizi", mainly made up of bornyl acetate and aliphatic hydrocarbons, was inactive in the antibacterial assay. Further study of the main compounds in "Yimucao oil" showed that β-caryophyllene had wide-spectrum activity against Gram-positive bacteria.

Indexed as

Anti-Bacterial AgentsDrugs, Chinese HerbalFruitGas Chromatography-Mass SpectrometryGram-Negative BacteriaGram-Positive BacteriaLeonurusMicrobial Sensitivity TestsOils, VolatilePlant Components, AerialPlant OilsTerpenesAnti-Bacterial AgentsDrugs, Chinese HerbalOils, VolatilePlant OilsTerpenes

Identifiers

PMID23344204
PMCPMC6270501
OpenAlexW1985830577

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.