ReviewWorld journal of surgical oncology2013
Symptomatic cardiac metastases of breast cancer 27 years after mastectomy: a case report with literature review--pathophysiology of molecular mechanisms and metastatic pathways, clinical aspects, diagnostic procedures and treatment modalities.
Review in World journal of surgical oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Complete Heart Block and Nonsustained Ventricular Tachycardia Secondary to Cardiac Metastases From Breast Cancer.JACC. Case reports · 2026Article
- Incidental Cardiac Metastasis in Breast Carcinoma.Diagnostics (Basel, Switzerland) · 2025Article
- Comprehensive understanding of a rare disease: Cardiac metastatic tumor, a double-center 10-year case review.World journal of cardiology · 2025Article
- Cardiac metastasis of triple-negative breast cancer mimicking myxoma: A case report.International journal of surgery case reports · 2021Article
- miR-126 reduces trastuzumab resistance by targeting PIK3R2 and regulating AKT/mTOR pathway in breast cancer cells.Journal of cellular and molecular medicine · 2020Article
- Cardiac Tumors:JACC. CardioOncology · 2020Review
- Rare sites of breast cancer metastasis: a review.Translational cancer research · 2019Review
- Solitary cardiac metastasis from primary oral squamous cell carcinoma presenting as ST-elevation MI.BMJ case reports · 2018Article
- Superior Vena Cava as Gateway to Heart: Metastatic Breast Carcinoma Causing Ball in a Loop Metastasis to Right Atrium.Journal of clinical and diagnostic research : JCDR · 2017Article
- Right cardiac intracavitary metastases from a primary intracranial myxofibrosarcoma.BMJ case reports · 2016Article
- Bilateral diffuse fluorodeoxyglucose uptake in thyroid gland diagnosed by fluorodeoxyglucose-positron emission tomography/computed tomography.World journal of nuclear medicine · 2014Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metastases to the heart and pericardium are rare but more common than primary cardiac tumours and are generally associated with a rather poor prognosis. Most cases are clinically silent and are undiagnosed in vivo until the autopsy. We present a female patient with a 27-year-old history of an operated primary breast cancer who was presented with dyspnoea, paroxysmal nocturnal dyspnoea and orthopnoea. The clinical signs and symptoms aroused suspicion of congestive heart failure. However, the cardiac metastases were detected during a routine cardiologic evaluation and confirmed with computed tomography imaging. Additionally, this paper outlines the pathophysiology of molecular and clinical mechanisms involved in the metastatic spreading, clinical presentation, diagnostic procedures and treatment of heart metastases. The present case demonstrates that a complete surgical resection and systemic chemotherapy may result in a favourable outcome for many years. However, a lifelong medical follow-up, with the purpose of a detection of metastases, is highly recommended. We strongly call the attention of clinicians to the fact that during the follow-up of all cancer patients, such heart failure may be a harbinger of the secondary heart involvement.
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