Evidence map›Paper›PMID 23343162›Full record

ReviewTherapeutic delivery2013

Nanomedicine in chemoradiation.

Seth M Miller, Andrew Z Wang

Abstract readReview
In one paragraph

Review in Therapeutic delivery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Review
  4. Review
  5. NQO1-dependent, Tumor-selective Radiosensitization of Non-small Cell Lung Cancers.Clinical cancer research : an official journal of the American Association for Cancer Research · 2019
    Article
  6. Review
  7. Article
  8. Nanotechnology in radiation oncology.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2014
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Seth M MillerDepartment of Radiation Oncology & Laboratory of Nano- & Translational Medicine, University of North Carolina, Chapel Hil, NC, USA.
Andrew Z Wang

Funding

Translational Nanosystems for Improved Lung Cancer Treatment with Small MoleculesU54CA151652 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ZHOU, OTTO Z · 2010 to 2014
$12.1M
UNC Oncology K12K12CA120780 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WILLIAM Y. KIM · 2007 to 2026
$9.6M
Nanoparticle formulations of DNA repair inhibitors to improve chemoradiotherapyR01CA178748 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WANG, ANDREW ZHUANG · 2013 to 2017
$1.6M
NCI NIH HHS 1-U54-CA151652-01NCI NIH HHS 5-K12-CA120780-01-05NCI NIH HHS K12 CA120780NCI NIH HHS R01 CA178748NCI NIH HHS U54 CA151652
6 · The paper itself

Abstract

Chemoradiotherapy, the concurrent administration of chemotherapy and radiotherapy, is a treatment paradigm in oncology. It is part of the standard of care and curative treatment of many cancers. Given its importance, one of the primary goals of cancer research has been to identify agents and/or strategies that can improve the therapeutic index of chemoradiation. Recent advances in nanomedicine have provided a unique and unprecedented opportunity for improving chemoradiotherapy. Nanoparticles possess properties that are ideally suited for delivering chemotherapy in the chemoradiation setting. The goal of this review is to examine the role of incorporating nanomedicine into chemoradiation and the potential impact of nanomedicine to chemoradiotherapy.

Indexed as

AnimalsAntineoplastic AgentsChemoradiotherapyHumansNanomedicineNanoparticlesNeoplasmsAntineoplastic Agents

Identifiers

PMID23343162
PMCPMC3652407

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.