Evidence map›Paper›PMID 23342373›Full record

ReviewViruses2012

Endocytic pathways involved in filovirus entry: advances, implications and future directions.

Suchita Bhattacharyya, Nirupama Mulherkar, Kartik Chandran

Abstract readReview
In one paragraph

Review in Viruses, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Marburg Virus Disease: A Narrative Review.Health science reports · 2025
    Article
  6. Review
  7. Mechanisms of Immune Evasion by Ebola Virus.Advances in experimental medicine and biology · 2021
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Suchita BhattacharyyaUniversity of Mumbai and Department of Atomic Energy-Centre for Excellence in Basic Sciences, Health Centre Building, Vidyanagari, Kalina, Santacruz East, Mumbai 400098, India. bsuchita@gmail.com
Nirupama Mulherkar
Kartik Chandran

Funding

Mechanisms of Ebolavirus and Marburgvirus Entry into CellsR01AI088027 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI CHANDRAN, KARTIK · 2010 to 2014
$2.0M
NIAID NIH HHS R01 AI088027NIAID NIH HHS R01AI088027
6 · The paper itself

Abstract

Detailed knowledge of the host-virus interactions that accompany filovirus entry into cells is expected to identify determinants of viral virulence and host range, and to yield targets for the development of antiviral therapeutics. While it is generally agreed that filovirus entry into the host cytoplasm requires viral internalization into acidic endosomal compartments and proteolytic cleavage of the envelope glycoprotein by endo/lysosomal cysteine proteases, our understanding of the specific endocytic pathways co-opted by filoviruses remains limited. This review addresses the current knowledge on cellular endocytic pathways implicated in filovirus entry, highlights the consensus as well as controversies, and discusses important remaining questions.

Indexed as

EndocytosisHost-Pathogen InteractionsVirus InternalizationAnimalsFiloviridaeHost SpecificityHumansVirulence FactorsVirulence Factors

Identifiers

PMID23342373
PMCPMC3528284

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.