ArticlePloS one2013
Transcriptomic immune response of Tenebrio molitor pupae to parasitization by Scleroderma guani.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
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- Chromatin condensation dynamics during spermatogenesis and variation in detectability and spatial distribution of satellite DNAs outside constitutive heterochromatin inFrontiers in insect science · 2026Article
- Comprehensive Analysis of Cathepsin Genes in Hemiptera: Functional Characterization of the Venomous Cathepsin B fromInsects · 2025Article
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- Omics in mini-livestock: a genomic perspective on the future of sustainable food systems.Frontiers in genetics · 2025Review
- Impacts of CombiningInsects · 2024Article
- Immune system modulation & virus transmission during parasitism identified by multi-species transcriptomics of a declining insect biocontrol system.BMC genomics · 2024Article
- Molecular Characterization and Functional Analysis of the Dipeptidyl Peptidase IV from Venom of the EctoparasitoidToxins · 2023Article
- Fossoriality in desert-adapted tenebrionid (Coleoptera) larvae.Scientific reports · 2022Article
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- Panaxadiol saponins treatment caused the subtle variations in the global transcriptional state of Asiatic corn borer,Journal of ginseng research · 2020Article
- Optimized pupal age of Tenebrio molitor L. (Coleoptera: Tenebrionidae) enhanced mass rearing efficiency of Chouioia cunea Yang (Hymenoptera: Eulophidae).Scientific reports · 2019Article
- Immune Defenses of a Beneficial Pest: The Mealworm Beetle,Frontiers in physiology · 2019Review
- Identification and Characterization of C-type Lectins in Ostrinia furnacalis (Lepidoptera: Pyralidae).Journal of insect science (Online) · 2018Article
- De Novo Assembly and Characterization of the Xenocatantops brachycerus Transcriptome.International journal of molecular sciences · 2018Article
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- Oral immune priming with Bacillus thuringiensis induces a shift in the gene expression of Tribolium castaneum larvae.BMC genomics · 2017Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHost and parasitoid interaction is one of the most fascinating relationships of insects, which is currently receiving an increasing interest. Understanding the mechanisms evolved by the parasitoids to evade or suppress the host immune system is important for dissecting this interaction, while it was still poorly known. In order to gain insight into the immune response of Tenebrio molitor to parasitization by Scleroderma guani, the transcriptome of T. molitor pupae was sequenced with focus on immune-related gene, and the non-parasitized and parasitized T. molitor pupae were analyzed by digital gene expression (DGE) analysis with special emphasis on parasitoid-induced immune-related genes using Illumina sequencing. METHODOLOGY/PRINCIPAL
findingsIn a single run, 264,698 raw reads were obtained. De novo assembly generated 71,514 unigenes with mean length of 424 bp. Of those unigenes, 37,373 (52.26%) showed similarity to the known proteins in the NCBI nr database. Via analysis of the transcriptome data in depth, 430 unigenes related to immunity were identified. DGE analysis revealed that parasitization by S. guani had considerable impacts on the transcriptome profile of T. molitor pupae, as indicated by the significant up- or down-regulation of 3,431 parasitism-responsive transcripts. The expression of a total of 74 unigenes involved in immune response of T. molitor was significantly altered after parasitization. CONCLUSIONS/SIGNIFICANCE: obtained T. molitor transcriptome, in addition to establishing a fundamental resource for further research on functional genomics, has allowed the discovery of a large group of immune genes that might provide a meaningful framework to better understand the immune response in this species and other beetles. The DGE profiling data provides comprehensive T. molitor immune gene expression information at the transcriptional level following parasitization, and sheds valuable light on the molecular understanding of the host-parasitoid interaction.
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