ArticlePloS one2013
Over-expression of VvWRKY1 in grapevines induces expression of jasmonic acid pathway-related genes and confers higher tolerance to the downy mildew.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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46 citing papers in PubMed, 121 citations in OpenAlex.
- Silica nanoparticles enhance resistance of Vitis vinifera to downy mildew.BMC plant biology · 2026Article
- GbWRKY11 Enhances Verticillium Wilt Resistance Through Activating Jasmonic Acid Biosynthesis in Cotton.Molecular plant pathology · 2026Article
- Genome and transcriptome analyses reveal molecular mechanisms underlying the interaction betweenFrontiers in plant science · 2026Article
- Transcriptome analysis reveals key pathways and regulatory networks involved in soybean's early resistance to Peronospora manshurica.BMC plant biology · 2025Article
- Plasmopara viticola Effector PvRXLR10 Targets a Host Phospholipase VvipPLA-IIδ2 to Suppress Plant Immunity in Grapevine.Molecular plant pathology · 2025Article
- Advances in the molecular mechanism of grapevine resistance to fungal diseases.Molecular horticulture · 2025Review
- Genome-Wide Identification, Characterisation, and Evolution of the Transcription Factor WRKY in Grapevine (International journal of molecular sciences · 2024Article
- Comparative Transcriptome Analysis between Resistant and Susceptible Pakchoi Cultivars in Response to Downy Mildew.International journal of molecular sciences · 2023Article
- Regulation of the regulators: Transcription factors controlling biosynthesis of plant secondary metabolites during biotic stresses and their regulation by miRNAs.Frontiers in plant science · 2023Review
- Transcriptome Profiling of the Resistance Response ofInternational journal of molecular sciences · 2022Article
- Exogenous melatonin increases salt tolerance in bitter melon by regulating ionic balance, antioxidant system and secondary metabolism-related genes.BMC plant biology · 2022Article
- Essential oil from Lavandula angustifolia elicits expression of three SbWRKY transcription factors and defense-related genes against sorghum damping-off.Scientific reports · 2022Article
- Review
- The Intragenesis and Synthetic Biology Approach towards Accelerating Genetic Gains on Strawberry: Development of New Tools to Improve Fruit Quality and Resistance to Pathogens.Plants (Basel, Switzerland) · 2021Article
- GRAS-domain transcription factor PAT1 regulates jasmonic acid biosynthesis in grape cold stress response.Plant physiology · 2021Article
- Transcriptional profiling reveals multiple defense responses in downy mildew-resistant transgenic grapevine expressing a TIR-NBS-LRR gene located at the MrRUN1/MrRPV1 locus.Horticulture research · 2021Article
- Responses to Drought Stress Modulate the Susceptibility toPlants (Basel, Switzerland) · 2021Article
- The Grapevine E3 Ubiquitin Ligase VriATL156 Confers Resistance against the Downy Mildew PathogenInternational journal of molecular sciences · 2021Article
- Biotechnological Approaches: Gene Overexpression, Gene Silencing, and Genome Editing to Control Fungal and Oomycete Diseases in Grapevine.International journal of molecular sciences · 2020Review
- Embryogenic callus induction andPlant biotechnology (Tokyo, Japan) · 2020Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Most WRKY transcription factors activate expression of defence genes in a salicylic acid- and/or jasmonic acid-dependent signalling pathway. We previously identified a WRKY gene, VvWRKY1, which is able to enhance tolerance to fungal pathogens when it is overexpressed in tobacco. The present work analyzes the effects of VvWRKY1 overexpression in grapevine. Microarray analysis showed that genes encoding defence-related proteins were up-regulated in the leaves of transgenic 35S::VvWRKY1 grapevines. Quantitative RT-PCR analysis confirmed that three genes putatively involved in jasmonic acid signalling pathway were overexpressed in the transgenic grapes. The ability of VvWRKY1 to trans-activate the promoters of these genes was demonstrated by transient expression in grape protoplasts. The resistance to the causal agent of downy mildew, Plasmopara viticola, was enhanced in the transgenic plants. These results show that VvWRKY1 can increase resistance of grapevine against the downy mildew through transcriptional reprogramming leading to activation of the jasmonic acid signalling pathway.
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