ArticlePloS one2013
Prevalence and risk factors of fluid overload in Southern Chinese continuous ambulatory peritoneal dialysis patients.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05721404 (Icodextrin Postpones the Shift of Low Dose to Full Dose Dialysis in the First Year of Incremental Peritoneal Dialysis), which is not on this map. Cited by 27 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Icodextrin Postpones the Shift of Low Dose to Full Dose Dialysis in the First Year of Incremental Peritoneal Dialysis: A Randomized Controlled Trial
Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 79 citations in OpenAlex.
- Effect of bioimpedance-defined overhydration parameters on mortality and cardiovascular events in patients undergoing dialysis: a systematic review and meta-analysis.The Journal of international medical research · 2021Pooled it
- Bioimpedance-defined overhydration predicts survival in end stage kidney failure (ESKF): systematic review and subgroup meta-analysis.Scientific reports · 2018Pooled it
- Comparison of Intradialytic Parenteral Nutrition with Glucose or Amino Acid Mixtures in Maintenance Hemodialysis Patients.Nutrients · 2016Trial
- Article
- Peritoneal protein clearance, fluid overload, and cardiovascular events in patients undergoing peritoneal dialysis: a prospective cohort study.Renal failure · 2025Article
- Article
- The Effect of a Novel Follow-up Mode Integrating Specialist Nurse-Led Care and an Intelligent Platform on Peritoneal Dialysis Patients.International journal of nephrology and renovascular disease · 2025Article
- Effects of Forearm Resistance Exercises on Breast Cancer-Related Lymphedema Using Segmental Bioelectrical Impedance Analysis: A Pilot Randomized Controlled Trial.Journal of clinical medicine · 2024Article
- Early Anuria in Incident Peritoneal Dialysis Patients: Incidence, Risk Factors, and Associated Clinical Outcomes.Kidney medicine · 2024Article
- Selection of dialysis methods for end-stage kidney disease patients with diabetes.World journal of diabetes · 2024Review
- Clinical risk factors for peritoneal dialysis withdrawal at different dialysis duration.Renal failure · 2023Article
- The association between office blood pressure and fluid status using bioimpedance spectroscopy in stable continuous ambulatory peritoneal dialysis patients.Clinical hypertension · 2022Article
- Peritoneal dialysis adequacy: a paradigm shift.Kidney research and clinical practice · 2022Article
- Obesity, Weight Gain, and Fluid Overload in Peritoneal Dialysis.Frontiers in nephrology · 2022Review
- Nutritional status and volume control in adolescents on chronic hemodialysis.Pediatric nephrology (Berlin, Germany) · 2021Article
- Article
- [Effect of salt intake on residual renal function in rats receiving peritoneal dialysis].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2021Article
- Gender-specific associations of skeletal muscle mass and arterial stiffness among peritoneal dialysis patients.Scientific reports · 2018Article
- Fluid Overload and Inflammation Axis.Blood purification · 2018Review
- Hydration health literacy in the elderly.Nutrition and healthy aging · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFluid overload is frequently present in CAPD patients and one of important predictors of mortality. The aim of this study is to investigate the prevalence and associated risk factors in a cohort study of Southern Chinese CAPD patients.
methodsThe patients (receiving CAPD 3 months and more) in our center were investigated from January 1, 2008 to December 31, 2009. Multi-frequency bioelectrical impedance analysis was used to assess the patient's body composition and fluid status.
resultsA total of 307 CAPD patients (43% male, mean age 47.8±15.3 years) were enrolled, with a median duration of PD 14.6 (5.9-30.9) months. Fluid overload (defined by Extracellular water/Total body water (ECW/TBW)≥0.40) was present in 205 (66.8%) patients. Univariate analysis indicated that ECW/TBW were inversely associated with body mass index (r = -0.11, P = 0.047), subjective global assessment score (r = -0.11, P = 0.004), body fat mass (r = -0.15, P = 0.05), serum albumin (r = -0.32, P<0.001), creatinine (r = -0.14, P = 0.02), potassium (r = -0.15, P = 0.02), and residual urine output (r = -0.14, P = 0.01), positively associated with age (r = 0.27, P<0.001), Chalrlson Comorbidity Index score (r = 0.29, P<0.001), and systolic blood pressure (r = 0.22, P<0.001). Multivariate linear regression showed that lower serum albumin (β = -0.223, P<0.001), lower body fat mass (β = -0.166, P = 0.033), old age (β = 0.268, P<0.001), higher systolic blood pressure (β = 0.16, P = 0.006), less residual urine output (β = -0.116, P = 0.042), and lower serum potassium (β = -0.126, P = 0.03) were independently associated with higher ECW/TBW. After 1 year of follow-up, the cardiac event rate was significantly higher in the patients with fluid overload (17.1% vs 6.9%, P = 0.023) than that of the normal hydrated patients.
conclusionsThe prevalence of fluid overload was high in CAPD patients. Fluid overload in CAPD patients were independently associated with protein-energy wasting, old age, and decreased residual urine output. Furthermore, CAPD patients with fluid overload had higher cardiac event rate than that of normal hydrated patents.
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