ArticleJournal of geriatric cardiology : JGC2012
Atrial fibrillation in the elderly: the potential contribution of reactive oxygen species.
Article in Journal of geriatric cardiology : JGC, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- Developing Pharmacological Therapies for Atrial Fibrillation Targeting Mitochondrial Dysfunction and Oxidative Stress: A Scoping Review.International journal of molecular sciences · 2023Article
- A Study of R-R Interval Transition Matrix Features for Machine Learning Algorithms in AFib Detection.Sensors (Basel, Switzerland) · 2023Article
- Relationship Between Radiation Exposure and Incident Atrial Fibrillation Among Atomic Bomb Survivors.Circulation reports · 2021Article
- Melatonin to Rescue the Aged Heart: Antiarrhythmic and Antioxidant Benefits.Oxidative medicine and cellular longevity · 2021Review
- Atrial fibrillation: risk factors and comorbidities in a tertiary center in Jeddah, Saudi Arabia.International journal of general medicine · 2019Article
- Red Wine, Resveratrol and Atrial Fibrillation.Nutrients · 2017Review
- Circulating ceruloplasmin, ceruloplasmin-associated genes, and the incidence of atrial fibrillation in the atherosclerosis risk in communities study.International journal of cardiology · 2017Article
- Authors' response.The Indian journal of medical research · 2015Article
- Association between red blood cell parameters & atrial fibrillation after acute myocardial infarction.The Indian journal of medical research · 2015Article
- Mitochondrial DNA 4977bp deletion mutation in peripheral blood reflects atrial remodeling in patients with non-valvular atrial fibrillation.Yonsei medical journal · 2015Article
- Pivotal roles of risk factors for incident atrial fibrillation in patients with newly diagnosed hyperthyroidism.Journal of geriatric cardiology : JGC · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Atrial fibrillation (AF) is the most commonly encountered cardiac arrhythmia, and is a significant source of healthcare expenditures throughout the world. It is an arrhythmia with a very clearly defined predisposition for individuals of advanced age, and this fact has led to intense study of the mechanistic links between aging and AF. By promoting oxidative damage to multiple subcellular and cellular structures, reactive oxygen species (ROS) have been shown to induce the intra- and extra-cellular changes necessary to promote the pathogenesis of AF. In addition, the generation and accumulation of ROS have been intimately linked to the cellular processes which underlie aging. This review begins with an overview of AF pathophysiology, and introduces the critical structures which, when damaged, predispose an otherwise healthy atrium to AF. The available evidence that ROS can lead to damage of these critical structures is then reviewed. Finally, the evidence linking the process of aging to the pathogenesis of AF is discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.