Evidence map›Paper›PMID 23341713›Full record

ArticleJournal of Korean medical science2013

Antimicrobial susceptibility of stenotrophomonas maltophilia isolates from Korea, and the activity of antimicrobial combinations against the isolates.

Hae-Sun Chung, Seong Geun Hong, Young Ree Kim, Kyeong Seob Shin, Dong Hee Whang, Jee Young Ahn, Yeon-Joon Park, Young Uh, Chulhun L Chang, Jong Hee Shin and 3 more

Abstract read
In one paragraph

Article in Journal of Korean medical science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  18. Frontiers in microbiology · 2017
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  19. Observational
  20. Surveillance of Dihydropteroate Synthase Genes inFrontiers in microbiology · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hae-Sun ChungDepartment of Laboratory Medicine and Research Institute of Antimicrobial Resistance, Yonsei University College of Medicine, Seoul, Korea.
Seong Geun Hong
Young Ree Kim
Kyeong Seob Shin
Dong Hee Whang
Jee Young Ahn
Yeon-Joon Park
Young Uh
Chulhun L Chang
Jong Hee Shin
Hye Soo Lee
Kyungwon Lee
Yunsop Chong

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to determine antimicrobial susceptibility of recent clinical Stenotrophomonas maltophilia isolates from Korea, and to compare the activity levels of several combinations of antimicrobials. A total of 206 non-duplicate clinical isolates of S. maltophilia was collected in 2010 from 11 university hospitals. Antimicrobial susceptibility testing was performed using the Clinical Laboratory Standards Institute agar dilution method. In vitro activity of antimicrobial combinations was tested using the checkerboard method. The susceptibility rates to trimethoprim-sulfamethoxazole and minocycline were 96% and 99%, respectively. The susceptibility rate to levofloxacin was 64%. All of four antimicrobial combinations showed synergy against many S. maltophilia isolates. A combination of trimethoprim-sulfamethoxazole plus ticarcillin-clavulanate was most synergistic among the combinations. None of the combinations showed antagonistic activity. Therefore, some of the combinations may be more useful than individual drugs in the treatment of S. maltophilia infection. Further clinical studies are warranted to validate our in vitro test results.

Indexed as

Anti-Infective AgentsGram-Negative Bacterial InfectionsHospitals, UniversityHumansLevofloxacinMicrobial Sensitivity TestsMinocyclineOfloxacinRepublic of KoreaStenotrophomonas maltophiliaTrimethoprim, Sulfamethoxazole Drug CombinationAnti-Infective AgentsLevofloxacinMinocyclineOfloxacinTrimethoprim, Sulfamethoxazole Drug CombinationCombination Drug TherapyStenotrophomonas maltophiliaTicarcillin-ClavulanateTrimethoprim-Sulfamethoxazole

Identifiers

PMID23341713
PMCPMC3546106

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.