Evidence map›Paper›PMID 23341529›Full record

SynthesisJournal of clinical oncology : official journal of the American Society of Clinical Oncology2013

Systematic review of acupuncture in cancer care: a synthesis of the evidence.

M Kay Garcia, Jennifer McQuade, Robin Haddad, Sonya Patel, Richard Lee, Peiying Yang, J Lynn Palmer, Lorenzo Cohen

4 registry-linked trialsOpen access · greenAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 121 papers, 32 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
121citing papers in PubMed, 32 pooled it
89.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02116218 nawithdrawnnot on this mapstarted 2014, after this paper: background citation

Assessment of Cancer Pain in Emergency Department in Traditional Chinese Medicine (TCM): A Study Protocol for a Clinical Trial

TypeinterventionalSponsorChanghua Christian HospitalRan2014 to 2014Enrolled0ConditionsNeoplasms, PainArmsacupuncture, Vaccaria seed
NCT02457039 nacompletednot on this mapstarted 2015, after this paper: background citation

An Assessor-Blinded, Randomised Controlled Trial of Acupuncture to Prevent Chemobrain in Breast Cancer Patients

TypeinterventionalSponsorThe University of Hong KongRan2015 to 2019Enrolled93ConditionsChemo-brain, Drug-Related Side Effects and Adverse Reactions, Mild Cognitive Impairment, Breast CancerArmsDense cranial electroacupuncture stimulation, Body acupuncture, Least acupuncture stimulation, Cytoxan-containing chemotherapy regimens
NCT02663063 nacompletednot on this mapstarted 2015, after this paper: background citation

The Application of Evidence-Based Chinese Complementary and Alternative Medicine (CAM) in Hospice Palliative Care in Taiwan-The Second and Third Year Project.

TypeinterventionalSponsorTaipei Veterans General Hospital, TaiwanRan2015 to 2017Enrolled60ConditionsCancerArmsSSP treatment
NCT02976558 naterminatednot on this mapstarted 2016, after this paper: background citation

Prospective Open Randomized Monocentric Two-armed Controlled Clinical Trial in Parallel Groups to Investigate the Influence of Complementary Medicine (CAM) Interventions on Quality of Life and The Treatment Process of Patients Undergoing Allogenic Stem Cell Transplantation

TypeinterventionalSponsorUniversity of Erlangen-Nürnberg Medical SchoolRan2016 to 2019Enrolled104ConditionsHematological Neoplasm, Graft-Versus-Host Disease, Depression, Stem Cell Transplant ComplicationsArmsClown theatrical Performance, Acupuncture, Music Therapy TaKeTiNa
3 · Its place in the literature

Who cites it

121 citing papers in PubMed, 32 syntheses or guidelines pooled it, 324 citations in OpenAlex.

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  5. Influence of acupuncture and moxibustion on gastrointestinal function and adverse events in gastric cancer patients after surgery and chemotherapy: a meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
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  6. Guideline
  7. 2023 MASCC/ESMO consensus antiemetic guidelines related to integrative and non-pharmacological therapies.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
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  9. Acupuncture for radiation-induced toxicity in head and neck squamous cell carcinoma: a systematic review based on PICO criteria.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
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  19. Guideline
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61 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

M Kay GarciaUniversity of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 0462, Houston, TX 77030, USA.
Jennifer McQuade
Robin Haddad
Sonya Patel
Richard Lee
Peiying Yang
J Lynn Palmer
Lorenzo Cohen
Melanoma Institute Australia · AU

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
International Center of TCM for CancerU19CA121503 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI COHEN, LORENZO · 2005 to 2010
$3.0M
NCI NIH HHS CA016672NCI NIH HHS CA121503NCI NIH HHS P30 CA016672NCI NIH HHS U19 CA121503
6 · The paper itself

Abstract

purposeMany cancer centers offer acupuncture services. To date, a comprehensive systematic review of acupuncture in cancer care has not been conducted. The purpose of this review was to evaluate the efficacy of acupuncture for symptom management in patients with cancer.

methodsMedline, Embase, CINAHL, Cochrane (all databases), Scopus, and PubMed were searched from inception through December 2011 for prospective randomized clinical trials (RCT) evaluating acupuncture for symptom management in cancer care. Only studies involving needle insertion into acupuncture points were included. No language limitations were applied. Studies were assessed for risk of bias (ROB) according to Cochrane criteria. Outcomes by symptom were designated as positive, negative, or unclear.

resultsA total of 2,151 publications were screened. Of those, 41 RCTs involving eight symptoms (pain, nausea, hot flashes, fatigue, radiation-induced xerostomia, prolonged postoperative ileus, anxiety/mood disorders, and sleep disturbance) met all inclusion criteria. One positive trial of acupuncture for chemotherapy-induced nausea and vomiting had low ROB. Of the remaining studies, eight had unclear ROB (four positive, three negative, and one with unclear outcomes). Thirty-three studies had high ROB (19 positive, 11 negative, and three with both positive and negative outcomes depending on the symptom).

conclusionAcupuncture is an appropriate adjunctive treatment for chemotherapy-induced nausea/vomiting, but additional studies are needed. For other symptoms, efficacy remains undetermined owing to high ROB among studies. Future research should focus on standardizing comparison groups and treatment methods, be at least single-blinded, assess biologic mechanisms, have adequate statistical power, and involve multiple acupuncturists.

Indexed as

Acupuncture TherapyAntineoplastic AgentsAnxietyEvidence-Based MedicineFatigueHot FlashesHumansIntestinal Pseudo-ObstructionMood DisordersNauseaNeoplasmsObserver VariationPainPain ManagementRadiotherapyRandomized Controlled Trials as TopicAntineoplastic Agents

Identifiers

PMID23341529
PMCPMC3577953
OpenAlexW2108067703

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.