ReviewCurrent neurology and neuroscience reports2013
Latest American and European updates on infantile spasms.
Review in Current neurology and neuroscience reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Latitudinal differences on the global epidemiology of infantile spasms: systematic review and meta-analysis.Orphanet journal of rare diseases · 2018Pooled it
- Infantile Spasms (West Syndrome): Integrating Genetic, Neurotrophic, and Hormonal Mechanisms Toward Precision Therapy.Medicina (Kaunas, Lithuania) · 2025Review
- CMTS-GNN: a cross-modal temporal-spectral graph neural network with cognitive network explainability.Frontiers in neurology · 2025Article
- Epidemiology of Epileptic Spasm and Affecting Factors on One-Year Prognosis: A Study in Tabriz Children's Hospital.Iranian journal of child neurology · 2025Article
- Radiographic and Tomographic Study of the Cranial Bones in Children with the Idiopathic Type of West Syndrome.Pediatric reports · 2024Article
- Case report: Sex-specific characteristics of epilepsy phenotypes associated with Xp22.31 deletion: a case report and review.Frontiers in genetics · 2023Article
- Molecular Dynamics of CYFIP2 Protein and Its R87C Variant Related to Early Infantile Epileptic Encephalopathy.International journal of molecular sciences · 2022Article
- Brain Magnetic Resonance Imaging Findings in Infantile Spasms.Neurology international · 2022Article
- Pulse Methylprednisolone with Oral Prednisolone versus Adrenocorticotropic Hormone in Children with West Syndrome: a Randomized Controlled Trial.Journal of epilepsy research · 2021Article
- West syndrome: a comprehensive review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020Review
- Neutrophil to lymphocyte rate and serum prealbumin maybe predictors for abnormal high blood pressure caused by adrenocorticotropic hormone therapy in children with epileptic spasms: two cases report.Annals of translational medicine · 2020Article
- Metabolic etiologies in West syndrome.Epilepsia open · 2018Review
- Benign and severe early-life seizures: a round in the first year of life.Italian journal of pediatrics · 2018Review
- [Immunological mechanism of prednisone in the treatment of infantile spasm].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2017Article
- Effectiveness and Safety of Different Once-Daily Doses of Adrenocorticotropic Hormone for Infantile Spasms.Paediatric drugs · 2017Article
- Non-invasive, multimodal analysis of cortical activity, blood volume and neurovascular coupling in infantile spasms using EEG-fNIRS monitoring.NeuroImage. Clinical · 2017Article
- Infantile spasms with periventricular nodular heterotopia, unbalanced chromosomal translocation 3p26.2 -10p15.1 and 6q22.31 duplication.Clinical case reports · 2016Article
- Neonatal hypoglycemic brain injury is a cause of infantile spasms.Experimental and therapeutic medicine · 2016Article
- Management of infantile spasms.Translational pediatrics · 2015Review
- Association analysis of polymorphisms of the CRHR1 gene with infantile spasms.Molecular medicine reports · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Infantile spasms remain a challenging condition to study and treat, and although they form the commonest epilepsy syndrome with onset in infancy, the challenge is broadened by the wide range of potential underlying causes. The field of study remains dynamic, with debates relating to case definitions and organising structures for classification of seizures and epilepsies in general, and a newly proposed genetic and biologic classification specifically for infantile spasms. There have been recent consensus statements, a Delphi process eliciting prioritised quality-of-care indicators, systematic reviews of treatment, and a survey of clinical practice in the USA. There is increasing evidence that longer duration of spasms is associated with poorer neurodevelopmental outcomes. It has taken many years to develop an animal model that reasonably represents infantile spasms, but there are now several animal models, and they are leading to innovative and valuable studies that suggest novel treatments.
Indexed as
Identifiers
23341252What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.