ArticleEndocrine2013
Serum 25-hydroxyvitamin D, parathyroid hormone, and their association with metabolic syndrome in Chinese.
Article in Endocrine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Insulin Resistance Is Inversely Associated with the Status of Vitamin D in Both Diabetic and Non-Diabetic Populations.Nutrients · 2021Pooled it
- Trial
- Trial
- No causal relationship between serum vitamin D levels and alcoholic liver disease: a two-sample bidirectional Mendelian randomization study.Frontiers in nutrition · 2024Article
- Gender specific association of parathyroid hormone and vitamin D with metabolic syndrome in population with preserved renal function.Scientific reports · 2018Article
- Effect of waist circumference on the association between serum 25-hydroxyvitamin D and serum lipids: results from the National Health and Nutrition Examination Survey 2001-2006.Public health nutrition · 2017Article
- Low vitamin D status is associated with advanced liver fibrosis in patients with nonalcoholic fatty liver disease.Endocrine · 2017Article
- Vitamin D Status Is Negatively Correlated with Insulin Resistance in Chinese Type 2 Diabetes.International journal of endocrinology · 2016Article
- Serum N(1)-Methylnicotinamide Is Associated With Obesity and Diabetes in Chinese.The Journal of clinical endocrinology and metabolism · 2015Article
- Hypovitaminosis D in adolescents living in the land of sun is correlated with incorrect life style: a survey study in Campania region.Endocrine · 2015Article
- Association between serum vitamin D, parathyroid hormone and metabolic syndrome in middle-aged and older Korean adults.European journal of clinical nutrition · 2015Article
- Increased low-density lipoprotein cholesterol level is associated with non-vertebral fractures in postmenopausal women.Endocrine · 2015Article
- Carotid intima-media thickness is not associated with vitamin D and PTH levels in patients admitted to an Internal Medicine Department.Endocrine · 2014Article
- Investigation of serum bisphenol A, vitamin D, and parathyroid hormone levels in patients with obstructive sleep apnea syndrome.Endocrine · 2014Article
- Serum levels of 25-hydroxyvitamin D are associated with cognitive impairment in type 2 diabetic adults.Endocrine · 2014Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Increasing evidence suggests that 25-hydroxyvitamin D [25(OH)D] and parathyroid hormone (PTH) levels are associated with metabolic syndrome (MetS). In 2010, we explored the association of serum 25(OH)D and PTH levels with MetS in 1,390 Chinese participants, aged 20-83 years. Anthropometric phenotypes, blood pressure, and the incidence of MetS were evaluated. In addition, serum lipids, 25(OH)D, and PTH were measured. The median concentration of 25(OH)D and PTH were 55.3 nmol/l and 2.8 pmol/l, respectively. The prevalence of vitamin D deficiency (<50 nmol/l) was 39.9 %, with 34.5 % in men and 47.8 % in women. After accounting for confounding factors and serum PTH, a 10 nmol/l higher serum 25(OH)D level was associated with a 10 % lower risk of MetS (OR = 0.90, 95 % CI 0.84-0.96, P = 0.0007). Furthermore, participants with vitamin D sufficiency had a 35 % lower risk of MetS than those with vitamin D deficiency (OR = 0.65, 95 % CI 0.51-0.84, P = 0.0009). PTH was not associated with the risk of MetS after adjustment for confounding factors. These results were confirmed in both men and women. Thus in this cohort of Chinese individuals, vitamin D deficiency is common and optimal vitamin D level is inversely associated with MetS, independent of several confounders and PTH level. The clinical significance of these findings warrants further study.
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