Trial reportTrials2013
Early treatment of posterior crossbite--a randomised clinical trial.
Trial report in Trials, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03353766 (The Effect of Timing on Lateral Crossbite Correction - a Randomized Study), which is not on this map. Cited by 16 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Timing on Lateral Crossbite Correction - a Randomized Study
Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Does Early Orthodontic Treatment in Mixed Dentition Improve Long-Term Outcomes? A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2025Pooled it
- The effectiveness of the early orthodontic correction of functional unilateral posterior crossbite in the mixed dentition period: a systematic review and meta-analysis.Progress in orthodontics · 2022Pooled it
- Orthodontic treatment for posterior crossbites.The Cochrane database of systematic reviews · 2021Pooled it
- Educational support and weekly telemonitoring during rapid maxillary expansion in children: a prospective preference-based comparative cohort study.Frontiers in dental medicine · 2026Article
- Dentoalveolar changes and transverse discrepancies through the treatment of class II division 1 malocclusion in children using a twin block device.Journal of clinical and experimental dentistry · 2025Article
- Early orthodontic treatment need over a 10-year period and evaluation of short-term intervention stability.Clinical oral investigations · 2024Article
- Prevalence of Malocclusions among Schoolchildren from Southwestern Romania.Diagnostics (Basel, Switzerland) · 2024Article
- Optimal Treatment Timing in Orthodontics: A Scoping Review.European journal of dentistry · 2024Article
- A systematic review: facial, dental and orthodontic findings and orofacial diagnostics in patients with FASD.Frontiers in pediatrics · 2023Review
- Risk Factors for High-Arched Palate and Posterior Crossbite at the Age of 5 in Children Born Very Preterm: EPIPAGE-2 Cohort Study.Frontiers in pediatrics · 2022Article
- Very early orthodontic treatment: when, why and how?Dental press journal of orthodontics · 2022Article
- Parental Satisfaction with Their Children's Rapid Palatal Expansion Treatment Provided by Orthodontists and Pediatric Dentists.Patient preference and adherence · 2021Article
- Early Orthodontic Treatments of Unilateral Posterior Crossbite: A Systematic Review.Journal of clinical medicine · 2020Review
- Is there an asymmetry of the condylar and coronoid processes of the mandible in individuals with unilateral crossbite?The Angle orthodontist · 2019Article
- Transverse Skeletal Effects of Rapid Maxillary Expansion in Pre and Post Pubertal Subjects: A Systematic Review.Open access Macedonian journal of medical sciences · 2019Review
- Prevalence of malocclusion and occlusal traits in the early mixed dentition in Shanghai, China.PeerJ · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this randomised clinical trial was to assess the effect of early orthodontic treatment in contrast to normal growth effects for functional unilateral posterior crossbite in the late deciduous and early mixed dentition by means of three-dimensional digital model analysis.
methodsThis randomised clinical trial was assessed to analyse the orthodontic treatment effects for patients with functional unilateral posterior crossbite in the late deciduous and early mixed dentition using a two-step procedure: initial maxillary expansion followed by a U-bow activator therapy. In the treatment group 31 patients and in the control group 35 patients with a mean age of 7.3 years (SD 2.1) were monitored. The time between the initial assessment (T1) and the follow-up (T2) was one year. The orthodontic analysis was done by a three-dimensional digital model analysis. Using the 'Digimodel' software, the orthodontic measurements in the maxilla and mandible and for the midline deviation, the overjet and overbite were recorded.
resultsSignificant differences between the control and the therapy group at T2 were detected for the anterior, median and posterior transversal dimensions of the maxilla, the palatal depth, the palatal base arch length, the maxillary arch length and inclination, the midline deviation, the overjet and the overbite.
conclusionsOrthodontic treatment of a functional unilateral posterior crossbite with a bonded maxillary expansion device followed by U-bow activator therapy in the late deciduous and early mixed dentition is an effective therapeutic method, as evidenced by the results of this RCT. It leads to three-dimensional therapeutically induced maxillary growth effects. Dental occlusion is significantly improved, and the prognosis for normal craniofacial growth is enhanced.
trial registrationRegistration trial DRKS00003497 on DRKS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.