Evidence map›Paper›PMID 23337627›Full record

ReviewEMBO reports2013

Non-autophagic roles of autophagy-related proteins.

Suresh Subramani, Vivek Malhotra

Abstract readReview
In one paragraph

Review in EMBO reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 154 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
154citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

154 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Guideline
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Exosomes, autophagy, and cancer: A complex triad.International journal of cancer · 2025
    Review
  9. Article
  10. Isolation and characterization ofAntimicrobial agents and chemotherapy · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Evolution of innate immunity: lessons from mammalian models shaping our current view of insect immunity.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2024
    Review
  16. Article
  17. Article
  18. ATG5 selectively engages virus-tethered BST2/tetherin in an LC3C-associated pathway.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  19. Article
  20. Article

94 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Suresh SubramaniSection of Molecular Biology, Division of Biological Sciences, University of California, San Diego, California 92093-0322, USA. ssubramani@ucsd.edu
Vivek Malhotra

Funding

Mechanisms Involved in PexophagyR01GM069373 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SUBRAMANI, SURESH · 2006 to 2013
$2.3M
NIGMS NIH HHS GM 069373NIGMS NIH HHS R01 GM069373
6 · The paper itself

Abstract

Autophagy and autophagy-related processes are fundamentally important in human health and disease. These processes are viewed primarily as cellular degradative pathways that recycle macromolecules and dysfunctional or redundant organelles into amino acids, sugars and lipids, especially during starvation. However, the ubiquitin-like autophagy proteins and other components of the autophagic machinery additionally participate in cellular reprogramming. We highlight these non-autophagic roles of autophagy proteins with the aim of drawing attention to this growing, but unexplored, research topic. We focus on the non-autophagic functions of autophagy proteins in cell survival and apoptosis, modulation of cellular traffic, protein secretion, cell signalling, transcription, translation and membrane reorganization.

Indexed as

AutophagySignal TransductionAdaptor Proteins, Signal TransducingAdipogenesisAnimalsAutophagy-Related Protein 12Autophagy-Related Protein 5Autophagy-Related Protein 7Autophagy-Related Protein 8 FamilyExocytosisHost-Pathogen InteractionsHumansIntracellular Signaling Peptides and ProteinsMicrofilament ProteinsMicrotubule-Associated ProteinsProtein TransportAdaptor Proteins, Signal TransducingATG12 protein, humanATG5 protein, humanATG7 protein, humanAutophagy-Related Protein 12Autophagy-Related Protein 5Autophagy-Related Protein 7Autophagy-Related Protein 8 FamilyGABARAPL2 protein, humanIntracellular Signaling Peptides and ProteinsMicrofilament ProteinsMicrotubule-Associated ProteinsSmall Ubiquitin-Related Modifier ProteinsUbiquitin-Activating Enzymes

Identifiers

PMID23337627
PMCPMC3566844

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.