Evidence map›Paper›PMID 23337481›Full record

ArticleJournal of critical care2013

Pediatric upper airway obstruction: interobserver variability is the road to perdition.

Robinder G Khemani, James B Schneider, Rica Morzov, Barry Markovitz, Christopher J L Newth

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Journal of critical care, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Heliox for croup in children.The Cochrane database of systematic reviews · 2021
    Pooled it
  2. Heliox for croup in children.The Cochrane database of systematic reviews · 2018
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Utility of Endotracheal Tube Cuff Pressure Monitoring in Mechanically Ventilated (MV) Children in Preventing Post-extubation Stridor (PES).Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2021
    Article
  8. Article
  9. Article
  10. Derivation and Validation of an Objective Effort of Breathing Score in Critically Ill Children.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2019
    Observational
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Robinder G KhemaniChildren's Hospital Los Angeles, Los Angeles CA 90027, USA. rkhemani@chla.usc.edu
James B Schneider
Rica Morzov
Barry Markovitz
Christopher J L Newth
Children's Hospital of Los Angeles · USUniversity of Southern California · USCohen Children's Medical Center · US

Funding

Minimally invasive techniques to measure upper airway obstruction in childrenK23HD075069 · NICHD · CHILDREN'S HOSPITAL OF LOS ANGELES · PI KHEMANI, ROBINDER · 2012 to 2016
$668k
NHLBI NIH HHS K23 HL103785NICHD NIH HHS K23 HD075069
6 · The paper itself

Abstract

purposeThe purposes of the study are to determine the interobserver variability in the clinical assessment of pediatric upper airway obstruction (UAO) and to explore how variability in assessment of UAO may contribute to risk factors and incidence of postextubation UAO. MATERIALS: This is a prospective trial in 2 tertiary care pediatric intensive care units. Bedside practitioners performed simultaneous, blinded UAO assessments on 112 children after endotracheal extubation.

resultsAgreement among respiratory therapists, pediatric intensive care nurses, and pediatric intensive care physicians was poor for cyanosis (κ = 0.01) and hypoxemia at rest (κ = 0.14) and fair for consciousness (κ = 0.27), air entry (κ = 0.32), hypoxemia with agitation (κ = 0.27), and pulsus paradoxus (κ = 0.23). When looking at "stridor" and "retractions," defined using more than 2 grades of severity from the Westley Croup Score, the interrelater reliability was moderate (κ = 0.43 and κ = 0.47, respectively). This could be improved marginally by dichotomizing the presence or absence of stridor (κ = 0.54) or retractions (κ = 0.53). The overall incidence of UAO after extubation (stridor plus retractions) could range from 7% to 22%, depending on how many providers were required to agree.

conclusionsPhysical findings routinely used for UAO have poor interobserver reliability among bedside providers. This variability may contribute to inconsistent findings regarding incidence, risk factors, and therapies for postextubation UAO.

Indexed as

Airway ExtubationIntensive Care Units, PediatricAirway ObstructionChildChild, PreschoolFemaleHumansInfantMaleObserver VariationProspective StudiesRespiratory SoundsRisk FactorsAirway obstructionEndotrachealIntensive careIntubationPediatrics

Identifiers

PMID23337481
PMCPMC3644547
OpenAlexW1972757373

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.