Evidence map›Paper›PMID 23337254›Full record

ReviewCurrent opinion in immunology2013

Materials based tumor immunotherapy vaccines.

Weiwei Aileen Li, David J Mooney

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in immunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 58 citations in OpenAlex.

  1. Review
  2. Review
  3. Frontiers in pharmacology · 2022
    Article
  4. Article
  5. Review
  6. Promotion of CTL epitope presentation by a nanoparticle with environment-responsive stability and phagolysosomal escape capacity.Journal of controlled release : official journal of the Controlled Release Society · 2020
    Article
  7. Rational vaccinology with spherical nucleic acids.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  8. Article
  9. Article
  10. Injectable, Tough Alginate Cryogels as Cancer Vaccines.Advanced healthcare materials · 2018
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Engineering opportunities in cancer immunotherapy.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Review
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Weiwei Aileen LiSchool of Engineering and Applied Sciences, Harvard University, 29 Oxford Street, 319 Pierce Hall, Cambridge, MA 02138, USA.
David J Mooney
Harvard University · US

Funding

Programming dendritic cells in concert with morphagen delivery for periodontal reR01DE019917 · NIDCR · HARVARD UNIVERSITY · PI KAWAI, TOSHIHISA, MOONEY, DAVID J · 2009 to 2013
$3.5M
NIDCR NIH HHS R01 DE019917
6 · The paper itself

Abstract

Immunotherapy is a promising approach for treating cancer. However, there are limitations inherent to current approaches which may be addressed by integrating them with biomaterial-based strategies. Material platforms have been fabricated to interact with immune cells through spatially controlled and temporally controlled delivery of immune modulators and to promote immune cell crosstalk. Particle vaccines have been developed to specifically target and deliver agents to organs, cells and subcellular compartments. These strategies have been shown to generate antigen-specific CTL responses and, in some cases, tumor regression. Therefore, collaboration between immunology and materials engineering is likely to result in the creation of strong vaccines to combat cancer in the future.

Indexed as

ImmunotherapyAnimalsCancer VaccinesHumansNeoplasmsCancer Vaccines

Identifiers

PMID23337254
PMCPMC3644528
OpenAlexW2018826140

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.