ArticleJournal of the International AIDS Society2013
A survey of paediatric HIV programmatic and clinical management practices in Asia and sub-Saharan Africa--the International epidemiologic Databases to Evaluate AIDS (IeDEA).
Article in Journal of the International AIDS Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- Availability of substance use screening and treatment within HIV clinical sites across seven geographic regions within the IeDEA consortium.The International journal on drug policy · 2024Article
- Article
- Article
- Time-varying age- and CD4-stratified rates of mortality and WHO stage 3 and stage 4 events in children, adolescents and youth 0 to 24 years living with perinatally acquired HIV, before and after antiretroviral therapy initiation in the paediatric IeDEA Global Cohort Consortium.Journal of the International AIDS Society · 2020Article
- Weight-for-age distributions among children with HIV on antiretroviral therapy in the International epidemiology Databases to Evaluate AIDS (IeDEA) multiregional consortium.BMC research notes · 2020Article
- Temporal Trends in Co-trimoxazole Use Among Children on Antiretroviral Therapy and the Impact of Co-trimoxazole on Mortality Rates in Children Without Severe Immunodeficiency.Journal of the Pediatric Infectious Diseases Society · 2019Article
- IeDEA-WHO Research-Policy Collaboration: contributing real-world evidence to HIV progress reporting and guideline development.Journal of virus eradication · 2018Article
- Global temporal changes in the proportion of children with advanced disease at the start of combination antiretroviral therapy in an era of changing criteria for treatment initiation.Journal of the International AIDS Society · 2018Article
- Using Observational Data to Inform HIV Policy Change for Children and Youth.Journal of acquired immune deficiency syndromes (1999) · 2018Observational
- Models of support for disclosure of HIV status to HIV-infected children and adolescents in resource-limited settings.Journal of the International AIDS Society · 2018Article
- Time to First-Line ART Failure and Time to Second-Line ART Switch in the IeDEA Pediatric Cohort.Journal of acquired immune deficiency syndromes (1999) · 2018Article
- Screening and management of mental health and substance use disorders in HIV treatment settings in low- and middle-income countries within the global IeDEA consortium.Journal of the International AIDS Society · 2018Article
- HIV Viral Load Suppression in Adults and Children Receiving Antiretroviral Therapy-Results From the IeDEA Collaboration.Journal of acquired immune deficiency syndromes (1999) · 2017Article
- Brief Report: Pediatric Cancer Burden and Treatment Resources Within the Pediatric IeDEA Consortium.Journal of acquired immune deficiency syndromes (1999) · 2017Article
- Incidence of Postsuppression Virologic Rebound in Perinatally HIV-Infected Asian Adolescents on Stable Combination Antiretroviral Therapy.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2017Article
- Transition from paediatric to adult care of adolescents living with HIV in sub-Saharan Africa: challenges, youth-friendly models, and outcomes.Journal of the International AIDS Society · 2017Article
- Optimal timing of antiretroviral treatment initiation in HIV-positive children and adolescents: a multiregional analysis from Southern Africa, West Africa and Europe.International journal of epidemiology · 2017Article
- Improving estimates of children living with HIV from the Spectrum AIDS Impact Model.AIDS (London, England) · 2017Article
- Early Height and Weight Changes in Children Using Cotrimoxazole Prophylaxis With Antiretroviral Therapy.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2016Article
- Antiretroviral Therapy in Severely Malnourished, HIV-infected Children in Asia.The Pediatric infectious disease journal · 2016Observational
Corrections and comments
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1 author.
Funding
Abstract
introductionThere are limited data on paediatric HIV care and treatment programmes in low-resource settings.
methodsA standardized survey was completed by International epidemiologic Databases to Evaluate AIDS paediatric cohort sites in the regions of Asia-Pacific (AP), Central Africa (CA), East Africa (EA), Southern Africa (SA) and West Africa (WA) to understand operational resource availability and paediatric management practices. Data were collected through January 2010 using a secure, web-based software program (REDCap).
resultsA total of 64,552 children were under care at 63 clinics (AP, N=10; CA, N=4; EA, N=29; SA, N=10; WA, N=10). Most were in urban settings (N=41, 65%) and received funding from governments (N=51, 81%), PEPFAR (N=34, 54%), and/or the Global Fund (N=15, 24%). The majority were combined adult-paediatric clinics (N=36, 57%). Prevention of mother-to-child transmission was integrated at 35 (56%) sites; 89% (N=56) had access to DNA PCR for infant diagnosis. African (N=40/53) but not Asian sites recommended exclusive breastfeeding up until 4-6 months. Regular laboratory monitoring included CD4 (N=60, 95%), and viral load (N=24, 38%). Although 42 (67%) sites had the ability to conduct acid-fast bacilli (AFB) smears, 23 (37%) sites could conduct AFB cultures and 18 (29%) sites could conduct tuberculosis drug susceptibility testing. Loss to follow-up was defined as >3 months of lost contact for 25 (40%) sites, >6 months for 27 sites (43%) and >12 months for 6 sites (10%). Telephone calls (N=52, 83%) and outreach worker home visits to trace children lost to follow-up (N=45, 71%) were common.
conclusionsIn general, there was a high level of patient and laboratory monitoring within this multiregional paediatric cohort consortium that will facilitate detailed observational research studies. Practices will continue to be monitored as the WHO/UNAIDS Treatment 2.0 framework is implemented.
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