ArticleFrontiers in neuroscience2012
Sex, receptors, and attachment: a review of individual factors influencing response to oxytocin.
Article in Frontiers in neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
61 citing papers in PubMed, 121 citations in OpenAlex.
- Four-week intranasal oxytocin administration reduces attachment avoidance in older women.Hormones and behavior · 2023Trial
- Effects of oxytocin administration on fear-potentiated acoustic startle in co-occurring PTSD and alcohol use disorder: A randomized clinical trial.Psychiatry research · 2022Trial
- Oxytocin facilitates valence-dependent valuation of social evaluation of the self.Communications biology · 2020Trial
- Intranasal oxytocin modulates brain responses to voice-identity recognition in typically developing individuals, but not in ASD.Translational psychiatry · 2020Trial
- A registered replication study on oxytocin and trust.Nature human behaviour · 2020Trial
- Effects of Oxytocin Administration on Cue-Induced Craving in Co-occurring Alcohol Use Disorder and PTSD: A Within-Participant Randomized Clinical Trial.Alcoholism, clinical and experimental research · 2019Trial
- Oxytocin alters patterns of brain activity and amygdalar connectivity by age during dynamic facial emotion identification.Neurobiology of aging · 2019Trial
- Effects of oxytocin on stress reactivity and craving in veterans with co-occurring PTSD and alcohol use disorder.Experimental and clinical psychopharmacology · 2019Trial
- Effects of oxytocin on cortisol reactivity and conflict resolution behaviors among couples with substance misuse.Psychiatry research · 2018Trial
- A 12-week randomized controlled trial of twice-daily intranasal oxytocin for social cognitive deficits in people with schizophrenia.Schizophrenia research · 2017Trial
- Intranasal oxytocin increases neural responses to social reward in post-traumatic stress disorder.Social cognitive and affective neuroscience · 2017Trial
- Oxytocin efficacy is modulated by dosage and oxytocin receptor genotype in young adults with high-functioning autism: a 24-week randomized clinical trial.Translational psychiatry · 2016Trial
- Oxytocin, but not vasopressin, impairs social cognitive ability among individuals with higher levels of social anxiety: a randomized controlled trial.Social cognitive and affective neuroscience · 2016Trial
- Vasopressin, but not oxytocin, increases empathic concern among individuals who received higher levels of paternal warmth: A randomized controlled trial.Psychoneuroendocrinology · 2015Trial
- Oxytocin-induced modulation of explicit and implicit visual perspective taking.Scientific reports · 2026Article
- Updated Freudian drive theory: childhood trauma, epigenetics, serotonin and beta endorphin.Frontiers in psychiatry · 2026Article
- Increased salivary oxytocin correlates with lower self-reported interoceptive accuracy in functional neurological disorders.Neurobiology of stress · 2025Article
- Exploring a Possible Interplay between Schizophrenia, Oxytocin, and Estrogens: A Narrative Review.Brain sciences · 2023Review
- From Oxytocin to Compassion: The Saliency of Distress.Biology · 2023Article
- Genetic and epigenetic effects on couple adjustment in context of romantic relationship: A scoping systematic review.Frontiers in genetics · 2023Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As discussed in the larger review in this special issue (MacDonald and Feifel), intranasal oxytocin (OT) is demonstrating a growing potential as a therapeutic agent in psychiatry. Importantly, research suggests that a variety of individual factors may influence a person's response to OT. In this mini-review, I provide a review of three: (1) sex and hormonal status; (2) genetic variation in aspects of the OT system (i.e., OT receptors); and (3) attachment history. Each of these factors will be important to monitor as we strive to develop a richer understanding of OT's role in human development, brain-based disease, and the potential for individualized, OT-targeted treatments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.