ArticleAmerican journal of physiology. Heart and circulatory physiology2013
Effect of stellate ganglia stimulation on global and regional left ventricular function as assessed by speckle tracking echocardiography.
Article in American journal of physiology. Heart and circulatory physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed.
- Closed-loop electrical block of vagus nerve scales from rodent to porcine cardiac models.Journal of neural engineering · 2025Article
- Topographical mapping of catecholaminergic axon innervation in the flat-mounts of the mouse atria: a quantitative analysis.Scientific reports · 2023Article
- Sympathetic Nervous System Mediates Cardiac Remodeling After Myocardial Infarction in a Circadian Disruption Model.Frontiers in cardiovascular medicine · 2021Article
- Asymmetry and Heterogeneity: Part and Parcel in Cardiac Autonomic Innervation and Function.Frontiers in physiology · 2021Review
- Effect of thoracic epidural anesthesia on heart rate variability in a porcine model.Physiological reports · 2017Article
- Central vs. peripheral neuraxial sympathetic control of porcine ventricular electrophysiology.American journal of physiology. Regulatory, integrative and comparative physiology · 2016Article
- Evaluation of left ventricular systolic strain in children with Kawasaki disease.Pediatric cardiology · 2014Article
- Modulation of regional dispersion of repolarization and T-peak to T-end interval by the right and left stellate ganglia.American journal of physiology. Heart and circulatory physiology · 2013Article
- Left ventricular twist and untwist rate provide reliable measures of ventricular function in myocardial ischemia and a wide range of hemodynamic states.Physiological reports · 2013Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Left ventricular (LV) twist mechanics and regional strain during cardiac sympathetic efferent activation are poorly understood. The purpose of this study was to compare the effects of left stellate ganglia (LSG) and right stellate ganglia (RSG) stimulation on cardiac twist/untiwst mechanics and regional strain. In nine pigs, echocardiographic imaging and LV pressure-volume measurements were performed before and during unilateral and bilateral stellate ganglion stimulation. LSG and RSG stimulation significantly augmented LV end-systolic pressure by 24% and 22% (P < 0.01), maximal rate of LV pressure change by 167% and 165% (P < 0.01), and time constant of LV relaxation by 20% and 12% (P < 0.01), respectively. RSG stimulation resulted in a greater chronotropic response than LSG stimulation (RSG: 68% vs. LSG: 12%, P < 0.01). Both LSG and RSG stimulation significantly increased global epicardial and endocardial LV rotation and diastolic untwisting rate and reduced the time to peak rotation (P < 0.05). However, LSG stimulation predominantly increased radial and circumferential strain in the LV inferoseptal, inferior, posterior, and lateral regions, whereas RSG stimulation primarily increased radial and circumferential strain in the anteroseptal, anterior, and lateral LV regions. Stimulation of both stellate ganglia led to a uniform increase in all LV segments. Our data suggest that LSG and RSG stimulation lead to a global increase in LV twist, driven by distinct regional strain heterogeneity that may result from myocardial innervation from the LSG and RSG. These findings provide a better understanding of the global and regional functional consequences of regional myocardial innervation from the LSG and RSG.
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