ArticleGenetics2013
Genetic dissection of a major anthocyanin QTL contributing to pollinator-mediated reproductive isolation between sister species of Mimulus.
Article in Genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
73 citing papers in PubMed, 159 citations in OpenAlex.
- LlR3MYB-mediated flavonoid biosynthesis confers cold stress tolerance inHorticulture research · 2026Article
- The genetic and developmental enigma of rhizomes: crucial traits with limited understanding.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Review
- Reproductive Barriers and Genomic Hotspots of Adaptation During Allopatric Species Divergence.Molecular ecology · 2025Article
- Characterization of a KANADI-like transcription factor that suppresses pear anthocyanin biosynthesis.Horticulture research · 2025Article
- Pollination niche shifts in sympatric globular cactiPlant diversity · 2025Article
- From spots to stripes: Evolution of pigmentation patterns in monkeyflowers via modulation of a reaction-diffusion system and its prepatterns.bioRxiv : the preprint server for biology · 2025Article
- Color, proximate composition, bioactive compounds and antinutrient profiling of rose.Scientific reports · 2024Article
- BLADE-ON-PETIOLE interacts with CYCLOIDEA to fine-tuneScience advances · 2024Article
- A distinct foliar pigmentation pattern formed by activator-repressor gradients upstream of an anthocyanin-activating R2R3-MYB.Cell reports · 2024Article
- Absence of long-term balancing selection on variation in EuMYB3, an R2R3-MYB gene responsible for the anther-color polymorphism in Erythronium umbilicatum.Scientific reports · 2024Article
- Genetics and the Evolution of Prezygotic Isolation.Cold Spring Harbor perspectives in biology · 2024Review
- Genetic basis of nectar guide trichome variation between bumblebee- and self-pollinated monkeyflowers (Mimulus): role of the MIXTA-like gene GUIDELESS.BMC plant biology · 2024Article
- The R2R3-MYB Transcriptional RepressorInternational journal of molecular sciences · 2024Article
- Cloned genes and genetic regulation of anthocyanin biosynthesis in maize, a comparative review.Frontiers in plant science · 2024Review
- Article
- Strong postmating reproductive isolation in Mimulus section Eunanus.Journal of evolutionary biology · 2023Article
- Evolutionary walks through flower colour space driven by gene expression inProceedings. Biological sciences · 2023Article
- Taxon-specific, phased siRNAs underlie a speciation locus in monkeyflowers.Science (New York, N.Y.) · 2023Article
- Metabolic profile and transcriptome reveal the mystery of petal blotch formation in rose.BMC plant biology · 2023Article
- To stripe or not to stripe: the origin of a novel foliar pigmentation pattern in monkeyflowers (Mimulus).The New phytologist · 2023Article
13 more citing papers are in PubMed but not listed here.
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5 authors at 1 institution in 1 country.
Funding
Abstract
Prezygotic barriers play a major role in the evolution of reproductive isolation, which is a prerequisite for speciation. However, despite considerable progress in identifying genes and mutations responsible for postzygotic isolation, little is known about the genetic and molecular basis underlying prezygotic barriers. The bumblebee-pollinated Mimulus lewisii and the hummingbird-pollinated M. cardinalis represent a classic example of pollinator-mediated prezygotic isolation between two sister species in sympatry. Flower color differences resulting from both carotenoid and anthocyanin pigments contribute to pollinator discrimination between the two species in nature. Through fine-scale genetic mapping, site-directed mutagenesis, and transgenic experiments, we demonstrate that a single-repeat R3 MYB repressor, ROSE INTENSITY1 (ROI1), is the causal gene underlying a major quantitative trait locus (QTL) with the largest effect on anthocyanin concentration and that cis-regulatory change rather than coding DNA mutations cause the allelic difference between M. lewisii and M. cardinalis. Together with the genomic resources and stable transgenic tools developed here, these results suggest that Mimulus is an excellent platform for studying the genetics of pollinator-mediated reproductive isolation and the molecular basis of morphological evolution at the most fundamental level-gene by gene, mutation by mutation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.