Evidence map›Paper›PMID 23334570›Full record

ReviewMolecules (Basel, Switzerland)2013

A review on anti-inflammatory activity of monoterpenes.

Rita de Cássia da Silveira e Sá, Luciana Nalone Andrade, Damião Pergentino de Sousa

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 186 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
186citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02796339 phase2completednot on this mapstarted 2016, after this paper: background citation

A Phase-II Clinical Trial on the Effectiveness of a Nutritional Supplement With Natural Mastiha in Inflammatory Bowel Diseases Patients.

TypeinterventionalSponsorHarokopio UniversityRan2016 to 2021Enrolled100ConditionsInflammatory Bowel DiseasesArmsMastiha, Placebo
NCT04605289 phase1 / phase2completednot on this mapstarted 2020, after this paper: background citation

Biochemical Efficacy of Cymbopogon Citratus Gel as Local Drug Delivery Agent in Reducing Matrix Metalloproteinase-8 Levels Intra-crevicularly in Moderate Periodontitis Patients

TypeinterventionalSponsorAlexandria UniversityRan2020 to 2020Enrolled40ConditionsPeriodontitisArmslemongrass essential oil gel, Placebo, Scaling and root planing
3 · Its place in the literature

Who cites it

186 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Efficacy and safety of AtusinBMC pulmonary medicine · 2025
    Trial
  4. Trial
  5. Trial
  6. Trial
  7. WildPlants (Basel, Switzerland) · 2026
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Phytochemical properties ofFrontiers in pharmacology · 2026
    Article
  18. Review
  19. Article
  20. Article

126 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rita de Cássia da Silveira e SáDepartment of Physiology and Pathology, Federal University of Paraíba, CP 5009, CEP 58051-970, João Pessoa, Paraíba, Brazil.
Luciana Nalone Andrade
Damião Pergentino de Sousa

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Faced with the need to find new anti-inflammatory agents, great effort has been expended on the development of drugs for the treatment of inflammation. This disorder reduces the quality of life and overall average productivity, causing huge financial losses. In this review the anti-inflammatory activity of 32 bioactive monoterpenes found in essential oils is discussed. The data demonstrate the pharmacological potential of this group of natural chemicals to act as anti-inflammatory drugs.

Indexed as

AnimalsAnti-Inflammatory AgentsCyclooxygenase InhibitorsHumansInflammation MediatorsMonoterpenesOils, VolatilePlant OilsPlants, MedicinalAnti-Inflammatory AgentsCyclooxygenase InhibitorsInflammation MediatorsMonoterpenesOils, VolatilePlant Oils

Identifiers

PMID23334570
PMCPMC6269770

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.