ArticleInternational journal of surgery case reports2013
Giant pancreatic insulinoma. The bigger the worse? Report of two cases and literature review.
Article in International journal of surgery case reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 15 citations in OpenAlex.
- Case Report: Giant insulinoma, a very rare tumor causing hypoglycemia.Frontiers in endocrinology · 2023Article
- Hypoglycemia in a Patient With a Polyhormonal Pancreatic Neuroendocrine Tumor With Evidence of Endocrine Progenitors.Journal of the Endocrine Society · 2018Article
- Concomitant existence of pheochromocytoma in a patient with multiple endocrine neoplasia type 1.Surgical case reports · 2016Article
- Giant insulinoma: report of a case and review of published reports.Surgical case reports · 2016Article
- Diagnosis and surgical management of insulinomas in 33 consecutive patients at a single institution.Langenbeck's archives of surgery · 2016Article
- Giant Malignant Insulinoma.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2016Article
- Giant insulinoma in a 15-year-old man: A case report.International journal of surgery case reports · 2016Article
- Hepatic arterial infusion combined with systemic chemotherapy induced complete response of metachronous liver metastases after resection of pancreatic insulinoma.Clinical journal of gastroenterology · 2013Article
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionGiant pancreatic insulinomas are rare endocrine tumors. We describe 2 cases reviewing the current literature. PRESENTATION OF CASE: We report herein 2 female patients affected by giant insulinomas of 14cm and 6cm, respectively. Symptomatic hypoglycemia episodes occurred during 4 months in first case and 3 years in the second one until diagnosis. Both patients were successfully treated performing a distal pancreatectomy with splenic preservation in the first case and a Whipple's procedure in the second one. DISCUSSION: Up to now only 7 cases have been reported previously. Insulinomas larger than 3cm accounts for less than 5% of all. This literature review shows that despite the size hypoglycemic symptoms varies from 1 day to 3 years and only 1 out of 9 cases reported presented lymph nodes metastases. No recurrences have been described.
conclusionOne of the cases here described (14cm) is the largest presented in the literature. Despite the size, giant insulinoma is related apparently neither to metastases nor to the recurrences.
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