ArticleJournal of neuroscience methods2013
FRET excited ratiometric oxygen sensing in living tissue.
Article in Journal of neuroscience methods, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The trial behind it
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Who cites it
21 citing papers in PubMed, 40 citations in OpenAlex.
- The impact of zwitterionic surfactants on optode-based nanosensorsThe Analyst · 2024Article
- Shining New Light on Biological Systems: Luminescent Transition Metal Complexes for Bioimaging and Biosensing Applications.Chemical reviews · 2024Review
- Triplet-Triplet Annihilation Upconversion-Based Oxygen Sensors to Overcome the Limitation of Autofluorescence.ACS sensors · 2023Article
- Microfluidic synthesis of quantum dots and their applications in bio-sensing and bio-imaging.Nanoscale advances · 2021Review
- Resonance Energy Transfer-Based Biosensors for Point-of-Need Diagnosis-Progress and Perspectives.Sensors (Basel, Switzerland) · 2021Review
- Difluoroboron β-diketonate polylactic acid oxygen nanosensors for intracellular neuronal imaging.Scientific reports · 2021Article
- Real-time physiological measurements of oxygen using a non-invasive self-referencing optical fiber microsensor.Nature protocols · 2020Article
- Mitochondrial dysfunction and role in spreading depolarization and seizure.Journal of computational neuroscience · 2019Article
- Quantum Dot-Dye Conjugates for Biosensing, Imaging, and Therapy.Advanced healthcare materials · 2018Review
- Astrocytic Kir4.1 channels and gap junctions account for spontaneous epileptic seizure.PLoS computational biology · 2018Article
- The influence of potassium concentration on epileptic seizures in a coupled neuronal model in the hippocampus.Cognitive neurodynamics · 2016Article
- The Role of Cell Volume in the Dynamics of Seizure, Spreading Depression, and Anoxic Depolarization.PLoS computational biology · 2015Article
- QD-Based FRET Probes at a Glance.Sensors (Basel, Switzerland) · 2015Review
- Role of multiple-scale modeling of epilepsy in seizure forecasting.Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society · 2015Review
- Imaging oxygen in neural cell and tissue models by means of anionic cell-permeable phosphorescent nanoparticles.Cellular and molecular life sciences : CMLS · 2015Article
- Nanoparticle-Based and Bioengineered Probes and Sensors to Detect Physiological and Pathological Biomarkers in Neural Cells.Frontiers in neuroscience · 2015Review
- Unification of neuronal spikes, seizures, and spreading depression.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Oxygen and seizure dynamics: II. Computational modeling.Journal of neurophysiology · 2014Article
- Oxygen and seizure dynamics: I. Experiments.Journal of neurophysiology · 2014Article
- Metabolic tumor profiling with pH, oxygen, and glucose chemosensors on a quantum dot scaffold.Inorganic chemistry · 2014Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Dynamic analysis of oxygen (O₂) has been limited by the lack of a real-time, quantitative, and biocompatible sensor. To address these demands, we designed a ratiometric optode matrix consisting of the phosphorescence quenching dye platinum (II) octaethylporphine ketone (PtOEPK) and nanocystal quantum dots (NQDs), which when embedded within an inert polymer matrix allows long-term pre-designed excitation through fluorescence resonance energy transfer (FRET). Depositing this matrix on various glass substrates allowed the development of a series of optical sensors able to measure interstitial oxygen concentration [O₂] with several hundred millisecond temporal resolution in varying biological microdomains of active brain tissue.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.