Evidence map›Paper›PMID 23332439›Full record

ArticleDrug and alcohol dependence2013

Integrating buprenorphine maintenance therapy into federally qualified health centers: real-world substance abuse treatment outcomes.

Marwan S Haddad, Alexei Zelenev, Frederick L Altice

4 registry-linked trialsAbstract readMulticenter Study
In one paragraph

Article in Drug and alcohol dependence, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 43 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 3 pooled it
5.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02496403 nacompletednot on this mapstarted 2015, after this paper: background citation

Buprenorphine and Substance Abuse Services for Prescription Opioid Dependence

TypeinterventionalSponsorKaiser PermanenteRan2015 to 2019Enrolled239ConditionsOpiate Substitution TreatmentArmsStandard Medical Management (SMM)
NCT04257214 naactive not recruitingnot on this mapstarted 2020, after this paper: background citation

Identifying Optimal Psychosocial Interventions for Patients Receiving Office-Based Buprenorphine

TypeinterventionalSponsorPhiladelphia College of Osteopathic MedicineRan2020 to 2026Enrolled340ConditionsOpioid Use DisorderArmsPsychosocial treatment
NCT04650386 nacompletednot on this mapstarted 2020, after this paper: background citation

Enhancing Office-based Buprenorphine Treatment: An Adaptive Psychosocial Approach

TypeinterventionalSponsorPublic Health Management CorporationRan2020 to 2024Enrolled125ConditionsOpioid-use DisorderArmsPsychosocial support determined by adaptive treatment algorithm
NCT06359340 naactive not recruitingnot on this mapstarted 2020, after this paper: background citation

Identifying Optimal Psychosocial Interventions for Patients Receiving Office-Based Buprenorphine

TypeinterventionalSponsorPublic Health Management CorporationRan2020 to 2026Enrolled440ConditionsOpioid-use DisorderArmsPsychosocial treatment
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 3 syntheses or guidelines pooled it, 78 citations in OpenAlex.

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  17. A Facility-Wide Plan to Increase Access to Medication for Opioid Use Disorder in Primary Care and General Mental Health Settings.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Marwan S HaddadCommunity Health Center, Inc., Middletown, CT, USA. haddadm@chc1.com
Alexei Zelenev
Frederick L Altice
Yale University · USCommunity Health Center · US

Funding

Using Coincidence Analysis to Investigate Factors Affecting PrEP Initiation and Continuation in Southern ending the Epidemic CountiesP30MH062294 · NIMH · YALE UNIVERSITY · PI John Edward Pachankis · 2001 to 2026
$48.5M
HIV, Buprenorphine, and the Criminal Justice SystemR01DA030768 · NIDA · YALE UNIVERSITY · PI ALTICE, FREDERICK LEWIS · 2010 to 2015
$4.0M
Enhancing Health Outcomes Among HIV+ Substance AbusersK24DA017072 · NIDA · YALE UNIVERSITY · PI ALTICE, FREDERICK LEWIS · 2003 to 2012
$1.5M
NIDA NIH HHS K24 DA017072NIDA NIH HHS R01 DA030768NIMH NIH HHS P30 MH062294
6 · The paper itself

Abstract

backgroundFew studies have examined real-world effectiveness of integrated buprenorphine maintenance treatment (BMT) programs in federally qualified health centers (FQHCs).

methodsOpioid dependent patients (N=266) inducted on buprenorphine between July 2007 and December 2008 were retrospectively assessed at Connecticut's largest FQHC network. Six-month BMT retention and opioid-free time were collected longitudinally from electronic health records; 136 (51.1%) of patients were followed for at least 12 months.

resultsParticipants had a mean age of 40.1 years, were primarily male (69.2%) and treated by family practitioners (70.3%). Co-morbidity included HCV infection (59.8%), mood disorders (71.8%) and concomitant cocaine use (59%). Retention on BMT was 56.8% at 6 months and 61.6% at 12 months for the subset observed over 1 year. Not being retained on BMT at 12 months was associated with cocaine use (AOR=2.18; 95% CI=1.35-3.50) while prescription of psychiatric medication (AOR=0.36; 95% CI 0.20-0.62) and receiving on-site substance abuse counseling (AOR=0.34; 95% CI 0.19, 0.59) improved retention. Two thirds of the participants experienced at least one BMT gap of 2 or more weeks with a mean gap length of 116.4 days.

conclusionsIntegrating BMT in this large FQHC network resulted in retention rates similarly reported in clinical trials and emphasizes the need for providing substance abuse counseling and screening for and treating psychiatric comorbidity.

Indexed as

Patient Protection and Affordable Care ActAdultBuprenorphineCohort StudiesConnecticutFemaleHumansLongitudinal StudiesMaintenance ChemotherapyMaleMiddle AgedOpioid-Related DisordersRetrospective StudiesSubstance Abuse Treatment CentersTreatment OutcomeYoung AdultBuprenorphine

Identifiers

PMID23332439
PMCPMC3674170
OpenAlexW2070913249

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.