ArticleThe American journal of medicine2013
Cardiovascular and noncardiovascular disease associations with hip fractures.
Article in The American journal of medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Bidirectional association between cardiovascular disease and hip fracture: a systematic review and meta-analysis.BMC cardiovascular disorders · 2025Pooled it
- Meta-analysis of hypertension and osteoporotic fracture risk in women and men.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017Pooled it
- Clopidogrel and hip fractures, is it safe? A systematic review and meta-analysis.BMC musculoskeletal disorders · 2016Pooled it
- Effects of ambient particulate matter pollution on daily hip fracture admissions in middle-aged and older adults: a time series study in Shantou, China.BMC public health · 2025Article
- Article
- Intensive Multiprofessional Rehabilitation Is Superior to Standard Orthogeriatric Care in Patients with Proximal Femur Fractures-A Matched Pair Study of 9580 Patients from the Registry for Geriatric Trauma (ATR-DGU).Journal of clinical medicine · 2024Article
- High blood pressure is associated with increased risk of future fracture, but not vice versa.Scientific reports · 2024Article
- Physical Activity and Activities of Daily Living in Older Adult Patients With Heart Failure Admitted for Subacute Musculoskeletal Disease.Annals of rehabilitation medicine · 2023Article
- The associations of markers of endothelial dysfunction with hip fracture risk.Archives of osteoporosis · 2023Article
- Predicting 30-Day and 180-Day Mortality in Elderly Proximal Hip Fracture Patients: Evaluation of 4 Risk Prediction Scores at a Level I Trauma Center.Diagnostics (Basel, Switzerland) · 2021Article
- Metabolic factors and hip fracture risk in a large Austrian cohort study.Bone reports · 2020Article
- The CANVAS Program: implications of canagliflozin on reducing cardiovascular risk in patients with type 2 diabetes mellitus.Cardiovascular diabetology · 2019Review
- Predicting mortality following hip fracture: an analysis of comorbidities and complications.Irish journal of medical science · 2015Article
- Length of sick leave as a risk marker of hip fracture: a nationwide cohort study from Sweden.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2015Article
- Proton pump inhibitors and risk of bone fractures.Current treatment options in gastroenterology · 2014Article
- Importance of frailty in patients with cardiovascular disease.European heart journal · 2014Review
- Temporal trends in the incidence of osteoporotic fractures.Current osteoporosis reports · 2013Review
- Poststroke hip fracture: prevalence, clinical characteristics, mineral-bone metabolism, outcomes, and gaps in prevention.Stroke research and treatment · 2013Article
- Effectiveness of treatment of transtrochanteric fractures with Dynamic Hip Screws using minimally invasive access.Revista brasileira de ortopediaArticle
- Transtrochanteric fractures: evaluation of data between hospital admission and discharge.Revista brasileira de ortopediaArticle
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
Abstract
backgroundThere is growing awareness of an association between cardiovascular disease and fractures, and a temporal increase in fracture risk after myocardial infarction has been identified. To further explore the nature of this relationship, we systematically examined the association of hip fracture with all disease categories and assessed related secular trends.
methodsBy using resources of the Rochester Epidemiology Project, a population-based incident case-control study was conducted. Disease history was compared among all Olmsted County, Minnesota, residents aged 50 years or more with a first radiographically confirmed hip fracture in 1985-2006 and community control subjects individually matched (1:1) to cases on age, sex, and index year (n = 3808; mean age, 82 years; standard deviation, 9 years; 76% were women).
resultsAll cardiovascular and numerous non-cardiovascular disease categories (eg, infectious diseases, nutritional and metabolic diseases, mental disorders, diseases of the nervous system and sense organs, and diseases of the respiratory system) were associated with fracture risk. However, increasing temporal trends were detected almost exclusively in cardiovascular disease categories. The largest increases in association were observed for ischemic heart disease, other forms of heart disease (including heart failure), hypertension, and diabetes, and were more pronounced among elderly women than other demographic subgroups.
conclusionsAlthough the association with hip fracture was not specific to cardiovascular disease, temporal increases were mainly detected in cardiometabolic diseases, all of which have been linked previously to frailty. This mechanism and others warrant further investigation.
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