ArticleEnvironmental science & technology2013
Paper-based electrochemiluminescent screening for genotoxic activity in the environment.
Article in Environmental science & technology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Recent Advances in Electrochemiluminescence Imaging Applications.Chemical & biomedical imaging · 2026Review
- Microfluidics on lensless, semiconductor optical image sensors: challenges and opportunities for democratization of biosensing at the micro-and nano-scale.Nanophotonics (Berlin, Germany) · 2023Review
- Paper-based analytical devices for point-of-need applications.Mikrochimica acta · 2023Review
- Porous Structural Microfluidic Device for Biomedical Diagnosis: A Review.Micromachines · 2023Review
- Paper based microfluidic devices: a review of fabrication techniques and applications.The European physical journal. Special topics · 2023Review
- Automated Immunoassay Performed on a 3D Microfluidic Paper-Based Device for Malaria Detection by Ambient Mass Spectrometry.Analytical chemistry · 2022Article
- Paper-Based Sensors: Emerging Themes and Applications.Sensors (Basel, Switzerland) · 2018Review
- Detecting Chemical Hazards in Foods Using Microfluidic Paper-Based Analytical Devices (μPADs): The Real-World Application.Micromachines · 2018Review
- Chemiluminescence assay for detection of 2-hydroxyfluorene using the G-quadruplex DNAzyme-HMikrochimica acta · 2017Article
- Automated 3-D Printed Arrays to Evaluate Genotoxic Chemistry: E-Cigarettes and Water Samples.ACS sensors · 2017Article
- Paper microchip with a graphene-modified silver nano-composite electrode for electrical sensing of microbial pathogens.Nanoscale · 2017Article
- Microchip-based ultrafast serodiagnostic assay for tuberculosis.Scientific reports · 2016Article
- Microfluidic array for simultaneous detection of DNA oxidation and DNA-adduct damage.The Analyst · 2016Article
- Advances in Microfluidic Paper-Based Analytical Devices for Food and Water Analysis.Micromachines · 2016Review
- Paper-based analytical devices for environmental analysis.The Analyst · 2016Review
- Electrochemistry-based approaches to low cost, high sensitivity, automated, multiplexed protein immunoassays for cancer diagnostics.The Analyst · 2016Review
- Paper-based electrochemical immunoassay for rapid, inexpensive cancer biomarker protein detection.Analytical methods : advancing methods and applications · 2014Article
- Voltammetric microwell array for oxidized guanosine in intact ds-DNA.Analytical chemistry · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
A low cost, microfluidic paper electrochemical device (μPED) was fabricated using screen printing of electrodes and heat transfer of patterned wax paper onto filter paper. The μPED features films of a light-emitting ruthenium metallopolymer, microsomal metabolic enzymes, and DNA to detect potential genotoxic pollutant activity in environmental samples. Unlike conventional analytical methods that detect specific pollutant compounds, the μPED was designed to rapidly measure the presence of genotoxic equivalents in environmental samples with the signal related to benzo[a]pyrene (B[a]P) as a reference standard. The analytical end point is the detection of DNA damage from metabolites produced in the device using an electrochemiluminescence output measured with a charge-coupled device (CCD) camera. Proof-of-concept of this measurement was established for smoke, water, and food samples. The μPED provides a rapid screening tool for on-site environmental monitoring that specifically monitors the genotoxic reactivity of metabolites of toxic compounds present in the samples.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.