ArticleAnalytical chemistry2013
Silver clusters as both chromophoric reporters and DNA ligands.
Article in Analytical chemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 53 citations in OpenAlex.
- Interactions of coinage metal nanoclusters with low-molecular-weight biocompounds.Biophysical reviews · 2024Review
- Bioconjugation of a Near-Infrared DNA-Stabilized Silver Nanocluster to Peptides and Human Insulin by Copper-Free Click Chemistry.Journal of the American Chemical Society · 2023Article
- Interrupted DNA and Slow Silver Cluster Luminescence.The journal of physical chemistry. C, Nanomaterials and interfaces · 2023Article
- Structure and luminescence of DNA-templated silver clusters.Nanoscale advances · 2021Review
- Article
- The spatial organization of trace silver atoms on a DNA template.RSC advances · 2020Review
- Label-free detection of microRNA: two-stage signal enhancement with hairpin assisted cascade isothermal amplification and light-up DNA-silver nanoclusters.Mikrochimica acta · 2020Article
- Footprints of Nanoscale DNA-Silver Cluster ChromophoresACS nano · 2019Article
- Switchable Dual-Emissive DNA-Stabilized Silver Nanoclusters.ACS omega · 2019Article
- The role of spacer sequence in modulating turn-on fluorescence of DNA-templated silver nanoclusters.Nucleic acids research · 2018Article
- Solvent Polarity-Dependent Behavior of Aliphatic Thiols and Amines toward Intriguingly Fluorescent AuAgGSH Assembly.ACS omega · 2017Article
- Ultrafast coherence transfer in DNA-templated silver nanoclusters.Nature communications · 2017Article
- MicroRNA Biomarkers in Neurodegenerative Diseases and Emerging Nano-Sensors Technology.Journal of movement disorders · 2017Review
- Locking-to-unlocking system is an efficient strategy to design DNA/silver nanoclusters (AgNCs) probe for human miRNAs.Nucleic acids research · 2016Article
- A Segregated, Partially Oxidized, and Compact Ag10 Cluster within an Encapsulating DNA Host.Journal of the American Chemical Society · 2016Article
- DNA-Protected Silver Clusters for Nanophotonics.Nanomaterials (Basel, Switzerland) · 2015Review
- DNA-Directed Fluorescence Switching of Silver Clusters.The journal of physical chemistry. C, Nanomaterials and interfaces · 2015Article
- A complementary palette of NanoCluster Beacons.ACS nano · 2014Article
- Near-infrared silver cluster optically signaling oligonucleotide hybridization and assembling two DNA hosts.Analytical chemistry · 2014Article
- A silver cluster-DNA equilibrium.Analytical chemistry · 2013Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Molecular silver clusters conjugated with DNA act as analyte sensors. Our studies evaluate a type of cluster-laden DNA strand whose structure and silver stoichiometry change with hybridization. The sensor strand integrates two functions: the 3' region binds target DNA strands through base recognition while the 5' sequence C(3)AC(3)AC(3)TC(3)A favors formation of a near-infrared absorbing and emitting cluster. This precursor form exclusively harbors an ∼11 silver atom cluster that absorbs at 400 nm and that condenses its single-stranded host. The 3' recognition site associates with a complementary target strand, thereby effecting a 330 nm red-shift in cluster absorption and a background-limited recovery of cluster emission at 790 nm. One factor underlying these changes is sensor unfolding and aggregation. Variations in salt and oligonucleotide concentrations control cluster development by influencing DNA association. Structural studies using fluorescence anisotropy, fluorescence correlation spectroscopy, and size exclusion chromatography show that the sensor-cluster conjugate opens and subsequently dimerizes with hybridization. A second factor contributing to the spectral and photophysical changes is cluster transformation. Empirical silver stoichiometries are preserved through hybridization, so hybridized, dimeric near-infrared conjugates host twice the amount of silver in relation to their violet absorbing predecessors. These DNA structure and net silver stoichiometry alterations provide insight into how DNA-silver conjugates recognize analytes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.