ArticleInternational journal of medical sciences2013
Inflammation and oxidative stress are associated with the prevalence of high aankle-brachial index in metabolic syndrome patients without chronic renal failure.
Article in International journal of medical sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Disparity in association of obesity measures with ankle and brachial systolic blood pressures in Europeans and South Asians.Scientific reports · 2022Article
- Abnormal Calcium Metabolism Mediated Increased Risk of Cardiovascular Events Estimated by High Ankle-Brachial Index in Patients on Peritoneal Dialysis.Frontiers in cardiovascular medicine · 2022Article
- IL-18 Mediates Vascular Calcification Induced by High-Fat Diet in Rats With Chronic Renal Failure.Frontiers in cardiovascular medicine · 2021Article
- Aortic Pulse Wave Velocity, Ankle-Brachial Index, and Malondialdehyde in Older Adults with or without Metabolic Syndrome.Pulse (Basel, Switzerland) · 2020Article
- Aquaporin 1 alleviates acute kidney injury via PI3K-mediated macrophage M2 polarization.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2020Article
- Apocynin attenuates angiotensin II-induced vascular smooth muscle cells osteogenic switching via suppressing extracellular signal-regulated kinase 1/2.Oncotarget · 2016Article
- Association of body mass index and left ventricular mass index with abnormally low and high ankle-brachial indices in chronic kidney disease.Hypertension research : official journal of the Japanese Society of Hypertension · 2016Article
- Using brachial-ankle pulse wave velocity to screen for metabolic syndrome in community populations.Scientific reports · 2015Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsHigh ankle-brachial index (ABI) is marker of increased cardiovascular morbidity and mortality, while the relationship and mechanism between high ABI and metabolic syndrome (MetS) are unclear. The objectives of this study were to determine the relationship and possible mechanism of MetS with high ABI.
methods341 participants without CRF were recruited. Among these participants, 58 participants (ABI ≥ 1.3) were include in high ABI group and the other 283 participants (0.9 < ABI < 1.3) were include in normal ABI group. Furthermore, these 341 participants were also divided into MetS group (n = 54) and non-MetS group (n = 287). All participants received examinations including body mass index (BMI), ABI and related biochemical parameters.
resultsCompared with non-MetS group, the prevalence of high ABI was higher in MetS group (27.8% vs. 15%, p < 0.05). Participants with 3-4 metabolic risk factors had higher prevalence of high ABI than those with 0-1 metabolic risk factors (27.8% vs. 12.7%, p < 0.05). The prevalence of high ABI in overweight participants was higher than those with normal body weight. And the participants with hypertension also had higher prevalence of high ABI than normotensive participants. BMI, high-sensitivity C-reactive protein (hsCRP) and superoxide dismutase (SOD) were all higher in high ABI group than normal ABI group (p < 0.05).
conclusionsMore metabolic risk factors have increased the risk of high ABI. Inflammation and oxidative stress are associated with prevalence of high ABI in metabolic syndrome patients without chronic renal failure.
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