ArticleMolecular biology and evolution2013
Lack of dosage compensation accompanies the arrested stage of sex chromosome evolution in ostriches.
Article in Molecular biology and evolution, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 47 citations in OpenAlex.
- Evolution of a ZW sex determination system in sticklebacks.Science advances · 2026Article
- RASA1 expression highlights Z/W dosage dynamics and gonadal development in chickens.BMC genomics · 2025Article
- Review
- Sex-biased gene content is associated with sex chromosome turnover in Danaini butterflies.Molecular ecology · 2024Article
- Chromatin accessibility, not 5mC methylation covaries with partial dosage compensation in crows.PLoS genetics · 2023Article
- The evolutionary maintenance of ancient recombining sex chromosomes in the ostrich.PLoS genetics · 2023Article
- New insights into Xenopus sex chromosome genomics from the Marsabit clawed frog X. borealis.Journal of evolutionary biology · 2022Article
- Chromosome-Level Genome Assembly Reveals Dynamic Sex Chromosomes in Neotropical Leaf-Litter Geckos (Sphaerodactylidae: Sphaerodactylus).The Journal of heredity · 2022Article
- Genetic Regulation of Avian Testis Development.Genes · 2021Review
- The avian W chromosome is a refugium for endogenous retroviruses with likely effects on female-biased mutational load and genetic incompatibilities.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Article
- Sex chromosome degeneration, turnover, and sex-biased expression of sex-linked transcripts in African clawed frogs (Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Article
- A frog with three sex chromosomes that co-mingle together in nature: Xenopus tropicalis has a degenerate W and a Y that evolved from a Z chromosome.PLoS genetics · 2020Article
- Why Do Some Sex Chromosomes Degenerate More Slowly Than Others? The Odd Case of Ratite Sex Chromosomes.Genes · 2020Article
- Regional epigenetic differentiation of the Z Chromosome between sexes in a female heterogametic system.Genome research · 2019Article
- Evolutionary Dynamics of Sex Chromosomes of Paleognathous Birds.Genome biology and evolution · 2019Article
- A Genetic Map of Ostrich Z Chromosome and the Role of Inversions in Avian Sex Chromosome Evolution.Genome biology and evolution · 2018Article
- Article
- Divergent Evolutionary Trajectories of Two Young, Homomorphic, and Closely Related Sex Chromosome Systems.Genome biology and evolution · 2018Article
- Conserved Patterns of Sex Chromosome Dosage Compensation in the Lepidoptera (WZ/ZZ): Insights from a Moth Neo-Z Chromosome.Genome biology and evolution · 2017Article
- Sequential Turnovers of Sex Chromosomes in African Clawed Frogs (G3 (Bethesda, Md.) · 2016Article
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2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sex chromosome evolution is usually seen as a process that, once initiated, will inevitably progress toward an advanced stage of degeneration of the nonrecombining chromosome. However, despite evidence that avian sex chromosome evolution was initiated >100 Ma, ratite birds have been trapped in an arrested stage of sex chromosome divergence. We performed RNA sequencing of several tissues from male and female ostriches and assembled the transcriptome de novo. A total of 315 Z-linked genes fell into two categories: those that have equal expression level in the two sexes (for which Z-W recombination still occurs) and those that have a 2-fold excess of male expression (for which Z-W recombination has ceased). We suggest that failure to evolve dosage compensation has constrained sex chromosome divergence in this basal avian lineage. Our results indicate that dosage compensation is a prerequisite for, not only a consequence of, sex chromosome evolution.
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