Evidence map›Paper›PMID 23329212›Full record

ReviewClinical reviews in allergy & immunology2014

Novel approaches to food allergy.

Yao-Hsu Yang, Bor-Luen Chiang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical reviews in allergy & immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. The Eosinophil in Health and Disease: from Bench to Bedside and Back.Clinical reviews in allergy & immunology · 2016
    Review
  5. Review
  6. The challenge of treating orphan disease.Clinical reviews in allergy & immunology · 2014
    Article
  7. The changing geoepidemiology of food allergies.Clinical reviews in allergy & immunology · 2014
    Review
  8. Phase 1 results of safety and tolerability in a rush oral immunotherapy protocol to multiple foods using Omalizumab.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2014
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Yao-Hsu YangDepartment of Pediatrics, National Taiwan University Hospital, College of Medicine, National Taiwan University, Number 8 Chung-Shan South Road, Taipei, 10061, Taiwan, yan0126@ms15.hinet.net.
Bor-Luen Chiang
National Taiwan University · TWNational Taiwan University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Food allergies have increased in recent decades. However, they cannot be effectively treated by the current management, which is limited to the identification and avoidance of foods that induce allergies and to the use of medicines for symptoms relief. To meet the medical need of prevention and cure of food allergies, several therapeutic strategies are under investigation. Some newly developed biologics such as anti-IgE antibody and anti-interleukin (IL)-5 antibody directed against significant molecules in the allergic process have shown their potential for the treatment of food allergies. Allergen-specific immunotherapy is the therapy that induces immune tolerance and may reduce the need for conventional medication, severity of allergic symptoms and eliminate hypersensitivity. In this article, clinical studies of immunotherapy via subcutaneous, oral, sublingual, and epicutaneous routes are extensively reviewed for their safety and effectiveness on various food allergies. In addition, to reduce the risk of anaphylaxis and increase toleragenic immunity, many studies are focusing on the modification of traditional allergens used for immunotherapy. Moreover, a Chinese herbal formulation with potential anti-allergic effects is being evaluated for its efficacy in patients with peanut allergy. Although more studies are needed, accumulated data of current studies represent compelling evidence of curative effects of some strategies and give a hope that food allergies are likely to be successfully treated in the future.

Indexed as

AllergensAntibodies, Anti-IdiotypicAntibodies, Monoclonal, HumanizedDesensitization, ImmunologicDrug Administration RoutesDrugs, Chinese HerbalFood HypersensitivityFruitHumansImmunoglobulin EImmunotherapyInterleukin-5VegetablesAllergensAntibodies, Anti-IdiotypicAntibodies, Monoclonal, Humanizedanti-IgE antibodiesDrugs, Chinese HerbalIL5 protein, humanImmunoglobulin EInterleukin-5mepolizumab

Identifiers

PMID23329212
OpenAlexW2001130670

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.