ReviewJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology2013
Stress and obesity as risk factors in cardiovascular diseases: a neuroimmune perspective.
Review in Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- Pooled it
- Trial
- Comorbidities and Inflammation: How Chronic Diseases Prime the Host Response in Sepsis.International journal of molecular sciences · 2026Review
- Association between basal metabolic rate and cognitive function in Chinese older adults: the mediating effect of sarcopenia.BMC geriatrics · 2025Article
- The Acute Inflammatory Effects of Weight Stigma: An Experimental Pilot Study.Stigma and health · 2025Article
- Metabolic syndrome and cardiovascular risk factors among bank employees in iran: a cross-sectional study.BMC public health · 2025Article
- Association between coffee consumption and metabolic syndrome: A cross-sectional and Mendelian randomization study.Journal of diabetes · 2024Article
- Exploring the Pathophysiology of Long COVID: The Central Role of Low-Grade Inflammation and Multisystem Involvement.International journal of molecular sciences · 2024Review
- Psychological stress and the longitudinal progression of subclinical atherosclerosis.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2024Article
- The sex-dependent response to psychosocial stress and ischaemic heart disease.Frontiers in cardiovascular medicine · 2023Review
- Maternal Immune Activation Hypotheses for Human Neurodevelopment: Some Outstanding Questions.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2022Review
- Novel insights into the pathological mechanisms of metabolic related dyslipidemia.Molecular biology reports · 2021Review
- Emerging functions of adipokines in linking the development of obesity and cardiovascular diseases.Molecular biology reports · 2020Review
- Cardiovascular Disease Disparities in Sexual Minority Adults: An Examination of the Behavioral Risk Factor Surveillance System (2014-2016).American journal of health promotion : AJHP · 2019Article
- Prior Repeated Stress Attenuates Cold-Induced Immunomodulation Associated with "Browning" in Mesenteric Fat of Rats.Cellular and molecular neurobiology · 2018Article
- Differential expression of six genes and correlation with fatness traits in a unique broiler population.Saudi journal of biological sciences · 2017Article
- Glucose intolerance after chronic stress is related with downregulated PPAR-γ in adipose tissue.Cardiovascular diabetology · 2016Article
- Article
- Dysfunctional brain-bone marrow communication: a paradigm shift in the pathophysiology of hypertension.Current hypertension reports · 2013Review
- The first Insubria autumn school on neuroimmunopharmacology: challenging paradigms beyond boundaries.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity is now growing at an alarming rate reaching epidemic proportions worldwide thus increasing morbidity and mortality rates for chronic disease. But although we have ample information on the complications associated with obesity, precisely what causes obesity remains poorly understood. Some evidence attributes a major role to a low-grade chronic inflammatory state (neurogenic inflammation) induced in obesity by inflammatory mediators produced and secreted within the expanded activated adipocyte pool. Adipose tissue is an endocrine organ that secretes numerous adipose tissue-specific or enriched hormones, known as adipokines, cytokine-like molecules thought to play a pathogenic role in cardiovascular diseases. The imbalance between increased inflammatory stimuli and decreased anti-inflammatory mechanisms may depend on chronic stress. Hence the positive correlation found between stress, obesity and cardiovascular diseases. The chronic inflammatory state associated with insulin resistance and endothelial dysfunction is highly deleterious for vascular function. This review focuses on the proposed neuroimmunodulatory mechanisms linking chronic (psychological) stress, obesity and cardiovascular diseases.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.