Evidence map›Paper›PMID 23329132›Full record

ArticleChemical communications (Cambridge, England)2013

Label-free electrochemical detection of an Entamoeba histolytica antigen using cell-free yeast-scFv probes.

Yadveer S Grewal, Muhammad J A Shiddiky, Sean A Gray, Kris M Weigel, Gerard A Cangelosi, Matt Trau

Open access · bronzeAbstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 63 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Yadveer S GrewalCentre for Biomarker Research and Development, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD 4072, Australia.
Muhammad J A Shiddiky
Sean A Gray
Kris M Weigel
Gerard A Cangelosi
Matt Trau
University of Queensland · AUSeattle University · USCenter for Infectious Disease Research · US

Funding

Accelerated molecular probe pipelineU01AI082186 · NIAID · UNIVERSITY OF WASHINGTON · PI CANGELOSI, GERARD A · 2009 to 2013
$4.7M
NIAID NIH HHS U01 AI082186NIAID NIH HHS U01AI082186-01
6 · The paper itself

Abstract

Inexpensive, simple and quick detection of pathogen antigens in human samples is a key global health objective. Limiting factors include the cost and complexity of diagnostic tests that utilize antibody probes. Herein, we present a method for label-free electrochemical detection of a protein from the enteric pathogen Entamoeba histolytica using cell-free yeast-embedded antibody-like fragments (yeast-scFv) as novel affinity reagents.

Indexed as

Electrochemical TechniquesAntigens, ProtozoanElectrodesElectron TransportEntamoeba histolyticaFerricyanidesGoldHumansImmunoassayRecombinant ProteinsSaccharomyces cerevisiaeSingle-Chain AntibodiesAntigens, ProtozoanFerricyanidesGoldhexacyanoferrate IIIRecombinant ProteinsSingle-Chain Antibodies

Identifiers

PMID23329132
PMCPMC3564640
OpenAlexW2066431198

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.