Evidence map›Paper›PMID 23327986›Full record

ReviewBioengineered

Bioengineered probiotics, a strategic approach to control enteric infections.

Mary Anne Roshni Amalaradjou, Arun K Bhunia

Open access · goldAbstract readReview
In one paragraph

Review in Bioengineered. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 68 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. The Gut Mycobiome for Precision Medicine.Journal of fungi (Basel, Switzerland) · 2025
    Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Anti-cancer activity of human gastrointestinal bacteria.Medical oncology (Northwood, London, England) · 2022
    Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mary Anne Roshni AmalaradjouMolecular Food Microbiology Laboratory; Department of Food Science; Purdue University; West Lafayette, IN USA; Department of Comparative Pathobiology; Purdue University; West Lafayette, IN USA.
Arun K BhuniaMolecular Food Microbiology Laboratory; Department of Food Science; Purdue University; West Lafayette, IN USA; Department of Comparative Pathobiology; Purdue University; West Lafayette, IN USA.
Purdue University West Lafayette · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enteric infections account for high morbidity and mortality and are considered to be the fifth leading cause of death at all ages worldwide. Seventy percent of all enteric infections are foodborne. Thus significant efforts have been directed toward the detection, control and prevention of foodborne diseases. Many antimicrobials including antibiotics have been used for their control and prevention. However, probiotics offer a potential alternative intervention strategy owing to their general health beneficial properties and inhibitory effects against foodborne pathogens. Often, antimicrobial probiotic action is non-specific and non-discriminatory or may be ineffective. In such cases, bioengineered probiotics expressing foreign gene products to achieve specific function is highly desirable. In this review we summarize the strategic development of recombinant bioengineered probiotics to control enteric infections, and to examine how scientific advancements in the human microbiome and their immunomodulatory effects help develop such novel and safe bioengineered probiotics.

Indexed as

AnimalsAnti-Infective AgentsBioengineeringBiotechnologyFoodborne DiseasesFood TechnologyHumansModels, AnimalProbioticsStress, PhysiologicalAnti-Infective Agentsbioengineered probioticsenteric infectionsfoodborne diseaseslactic acid bacteriaprobioticsrecombinant probiotics

Identifiers

PMID23327986
PMCPMC3937199
OpenAlexW2075129862

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.