ReviewChinese journal of cancer2013
Skeletal metastasis: treatments, mouse models, and the Wnt signaling.
Review in Chinese journal of cancer, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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Who cites it
22 citing papers in PubMed.
- 125I brachytherapy in the palliation of painful bone metastases from lung cancer after failure or rejection of conventional treatments.Oncotarget · 2016Trial
- Bone turnover markers as predictors of hypocalcemia in patients with bone metastases receiving denosumab.JBMR plus · 2025Article
- The Role of Osteoprotegerin in Breast Cancer: Genetic Variations, Tumorigenic Pathways, and Therapeutic Potential.Cancers · 2025Review
- Identification of Biomarkers Associated With Paget's Disease of Bone and Bone Metastasis From Breast Cancer Patients.Cancer reports (Hoboken, N.J.) · 2024Article
- Targeting nanoplatform synergistic glutathione depletion-enhanced chemodynamic, microwave dynamic, and selective-microwave thermal to treat lung cancer bone metastasis.Bioactive materials · 2024Article
- Automated detection of lung cancer-caused metastasis by classifying scintigraphic images using convolutional neural network with residual connection and hybrid attention mechanism.Insights into imaging · 2022Article
- Review
- Punicalin Attenuates Breast Cancer-Associated Osteolysis by Inhibiting the NF-κB Signaling Pathway of Osteoclasts.Frontiers in pharmacology · 2021Article
- Bone-seeking nanoplatform co-delivering cisplatin and zoledronate for synergistic therapy of breast cancer bone metastasis and bone resorption.Acta pharmaceutica Sinica. B · 2020Article
- WNT2-Mediated FZD2 Stabilization Regulates Esophageal Cancer Metastasis via STAT3 Signaling.Frontiers in oncology · 2020Article
- Gold clusters prevent breast cancer bone metastasis by suppressing tumor-induced osteoclastogenesis.Theranostics · 2020Article
- Effect of denosumab versus zoledronic acid on calcium levels in cancer patients with bone metastasis: A retrospective cohort study.Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners · 2019Article
- Ubiquitylation and degradation of adenomatous polyposis coli by MKRN1 enhances Wnt/β-catenin signaling.Oncogene · 2018Article
- Understanding the Progression of Bone Metastases to Identify Novel Therapeutic Targets.International journal of molecular sciences · 2018Review
- Inhibition of cancer cell migration with CuS@ mSiOInternational journal of nanomedicine · 2018Article
- Prodigiosin inhibits Wnt/β-catenin signaling and exerts anticancer activity in breast cancer cells.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- A simple selection-free method for detecting disseminated tumor cells (DTCs) in murine bone marrow.Oncotarget · 2016Article
- Radiotherapy cannot prolong overall survival of young prostate cancer patients with bone metastases.Journal of translational medicine · 2016Article
- Wnt3a: functions and implications in cancer.Chinese journal of cancer · 2015Review
- Challenging role of Wnt5a and its signaling pathway in cancer metastasis (Review).Experimental and therapeutic medicine · 2014Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Skeletal metastases result in significant morbidity and mortality. This is particularly true of cancers with a strong predilection for the bone, such as breast, prostate, and lung cancers. There is currently no reliable cure for skeletal metastasis, and palliative therapy options are limited. The Wnt signaling pathway has been found to play an integral role in the process of skeletal metastasis and may be an important clinical target. Several experimental models of skeletal metastasis have been used to find new biomarkers and test new treatments. In this review, we discuss pathologic process of bone metastasis, the roles of the Wnt signaling, and the available experimental models and treatments.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.