ArticleBMC research notes2013
Stromal protein degradation is incomplete in Arabidopsis thaliana autophagy mutants undergoing natural senescence.
Article in BMC research notes, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 30 citations in OpenAlex.
- Selective degradation processes in plants are not limited to autophagy.Plant cell reports · 2026Review
- RETICULATA1 is a plastid-localized basic amino acid transporter.Nature plants · 2025Article
- An Overview of the Molecular Mechanisms and Functions of Autophagic Pathways in Plants.Plant signaling & behavior · 2021Article
- Chloroplast dismantling in leaf senescence.Journal of experimental botany · 2021Review
- Transcriptome Analyses Throughout Chili Pepper Fruit Development Reveal Novel Insights into the Domestication Process.Plants (Basel, Switzerland) · 2021Article
- Autophagy controls resource allocation and protein storage accumulation in Arabidopsis seeds.Journal of experimental botany · 2018Article
- Programmed chloroplast destruction during leaf senescence involves 13-lipoxygenase (13-LOX).Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Origin of the Autophagosomal Membrane in Plants.Frontiers in plant science · 2016Review
- The endosomal protein CHARGED MULTIVESICULAR BODY PROTEIN1 regulates the autophagic turnover of plastids in Arabidopsis.The Plant cell · 2015Article
- Senescence-Associated Vacuoles, a Specific Lytic Compartment for Degradation of Chloroplast Proteins?Plants (Basel, Switzerland) · 2014Review
- Identification of predominant genes involved in regulation and execution of senescence-associated nitrogen remobilization in flag leaves of field grown barley.Journal of experimental botany · 2014Article
- Degradation of organelles or specific organelle components via selective autophagy in plant cells.International journal of molecular sciences · 2014Review
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundDegradation of highly abundant stromal proteins plays an important role in the nitrogen economy of the plant during senescence. Lines of evidence supporting proteolysis within the chloroplast and outside the chloroplast have been reported. Two extra-plastidic degradation pathways, chlorophagy and Rubisco Containing Bodies, rely on cytoplasmic autophagy.
resultsIn this work, levels of three stromal proteins (Rubisco large subunit, chloroplast glutamine synthetase and Rubisco activase) and one thylakoid protein (the major light harvesting complex protein of photosystem II) were measured during natural senescence in WT and in two autophagy T-DNA insertion mutants (atg5 and atg7). Thylakoid-localized protein decreased similarly in all genotypes, but stromal protein degradation was incomplete in the two atg mutants. In addition, degradation of two stromal proteins was observed in chloroplasts isolated from mid-senescence leaves.
conclusionsThese data suggest that autophagy does contribute to the complete proteolysis of stromal proteins, but does not play a major degenerative role. In addition, support for in organello degradation is provided.
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