ArticleeLife2013
Quantification of gait parameters in freely walking wild type and sensory deprived Drosophila melanogaster.
Article in eLife, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 122 papers, 1 of them a synthesis that pooled it.
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Who cites it
122 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The evolutionary trajectory of drosophilid walking.Current biology : CB · 2022Pooled it
- Cross-species identification of conserved and divergent locomotor kinematic strategies using AutoGaitA.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Quasi-static force requirements are not sufficient to explain arolium engagement in climbing Argentine ants.The Journal of experimental biology · 2026Article
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- Whole-body 3D kinematics of freely behavingbioRxiv : the preprint server for biology · 2026Article
- Proprioceptive limit detectors contribute to sensorimotor control of the Drosophila leg.Nature communications · 2026Article
- Inhibitory circuits control leg movements duringeLife · 2026Article
- The TRP-channel painless mediates substrate stiffness sensing in the legs during Drosophila oviposition.PLoS genetics · 2025Article
- Inhibitory circuits control leg movements duringbioRxiv : the preprint server for biology · 2025Article
- GABAergic neuronal dysfunction underlies tremor in spinocerebellar ataxia 3.Disease models & mechanisms · 2025Article
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- Sensorimotor delays constrain robust locomotion in a 3D kinematic model of fly walking.bioRxiv : the preprint server for biology · 2025Article
- Natural variability and individuality of walking behavior in Drosophila.The Journal of experimental biology · 2024Article
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- Miniature linear and split-belt treadmills reveal mechanisms of adaptive motor control in walking Drosophila.Current biology : CB · 2024Article
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- Presynaptic inhibition selectively suppresses leg proprioception in behavingbioRxiv : the preprint server for biology · 2024Article
- Comparative analysis of tardigrade locomotion across life stage, species, and disulfiram treatment.PloS one · 2024Article
- Fine-grained descending control of steering in walkingbioRxiv : the preprint server for biology · 2023Article
62 more citing papers are in PubMed but not listed here.
Corrections and comments
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- Erratum issued
Authors and funding
5 authors.
Funding
Abstract
Coordinated walking in vertebrates and multi-legged invertebrates [corrected] such as Drosophila melanogaster requires a complex neural network coupled to sensory feedback. An understanding of this network will benefit from systems such as Drosophila that have the ability to genetically manipulate neural activities. However, the fly's small size makes it challenging to analyze walking in this system. In order to overcome this limitation, we developed an optical method coupled with high-speed imaging that allows the tracking and quantification of gait parameters in freely walking flies with high temporal and spatial resolution. Using this method, we present a comprehensive description of many locomotion parameters, such as gait, tarsal positioning, and intersegmental and left-right coordination for wild type fruit flies. Surprisingly, we find that inactivation of sensory neurons in the fly's legs, to block proprioceptive feedback, led to deficient step precision, but interleg coordination and the ability to execute a tripod gait were unaffected.DOI:http://dx.doi.org/10.7554/eLife.00231.001.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.