ArticlePloS one2013
A laterally acquired galactose oxidase-like gene is required for aerial development during osmotic stress in Streptomyces coelicolor.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 34 citations in OpenAlex.
- Expansion of Auxiliary Activity Family 5 sequence space via biochemical characterization of six new copper radical oxidases.Applied and environmental microbiology · 2024Article
- Building a Cell House from Cellulose: The Case of the Soil AcidobacteriumMicroorganisms · 2022Article
- Role for a Lytic Polysaccharide Monooxygenase in Cell Wall Remodeling in Streptomyces coelicolor.mBio · 2022Article
- Weaving of bacterial cellulose by the Bcs secretion systems.FEMS microbiology reviews · 2022Review
- Teichoic acids anchor distinct cell wall lamellae in an apically growing bacterium.Communications biology · 2020Article
- Subtilisin-Involved Morphology Engineering for Improved Antibiotic Production in Actinomycetes.Biomolecules · 2020Article
- Production of Galactose Oxidase Inside the Fusarium fujikuroi Species Complex and Recombinant Expression and Characterization of the Galactose Oxidase GaoA Protein from Fusarium subglutinans.Molecular biotechnology · 2019Article
- Genome-Wide Mutagenesis Links Multiple Metabolic Pathways with Actinorhodin Production in Streptomyces coelicolor.Applied and environmental microbiology · 2019Article
- A family AA5_2 carbohydrate oxidase from Penicillium rubens displays functional overlap across the AA5 family.PloS one · 2019Article
- Morphology-driven downscaling of Streptomyces lividans to micro-cultivation.Antonie van Leeuwenhoek · 2018Article
- Cell-Biological Studies of Osmotic Shock Response in Streptomyces spp.Journal of bacteriology · 2017Article
- Heterogeneity in the Histidine-brace Copper Coordination Sphere in Auxiliary Activity Family 10 (AA10) Lytic Polysaccharide Monooxygenases.The Journal of biological chemistry · 2016Article
- Aggregation of germlings is a major contributing factor towards mycelial heterogeneity of Streptomyces.Scientific reports · 2016Article
- Recent advances in understandingF1000Research · 2016Review
- The DyP-type peroxidase DtpA is a Tat-substrate required for GlxA maturation and morphogenesis in Streptomyces.Open biology · 2016Article
- Article
- A small-scale proteomic approach reveals a survival strategy, including a reduction in alkaloid biosynthesis, in Hyoscyamus albus roots subjected to iron deficiency.Frontiers in plant science · 2013Article
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Phylogenetic reconstruction revealed that most Actinobacterial orthologs of S. coelicolor SCO2837, encoding a metal-dependent galactose oxidase-like protein, are found within Streptomyces and were probably acquired by horizontal gene transfer from fungi. Disruption of SCO2837 (glxA) caused a conditional bld phenotype that could not be reversed by extracellular complementation. Studies aimed at characterising the regulation of expression of glxA showed that it is not a target for other bld genes. We provide evidence that glxA is required for osmotic adaptation, although independently from the known osmotic stress response element SigB. glxA has been predicted to be part of an operon with the transcription unit comprising the upstream cslA gene and glxA. However, both phenotypic and expression studies indicate that it is also expressed from an independent promoter region internal to cslA. GlxA displays an in situ localisation pattern similar to that one observed for CslA at hyphal tips, but localisation of the former is independent of the latter. The functional role of GlxA in relation to CslA is discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.