Trial reportPloS one2013
Guided self-help cognitive behavioural therapy for depression in primary care: a randomised controlled trial.
Trial report in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 63 citations in OpenAlex.
- Discovering Common Elements of Empirically Supported Self-Help Interventions for Depression in Primary Care: a Systematic Review.Journal of general internal medicine · 2021Pooled it
- Cognitive behavioral therapy for primary care depression and anxiety: a secondary meta-analytic review using robust variance estimation in meta-regression.Journal of behavioral medicine · 2019Pooled it
- Helping patients help themselves: A systematic review of self-management support strategies in primary health care practice.PloS one · 2019Pooled it
- A Therapeutic Relational Agent for Reducing Problematic Substance Use (Woebot): Development and Usability Study.Journal of medical Internet research · 2021Trial
- Web-Based Intervention Using Behavioral Activation and Physical Activity for Adults With Depression (The eMotion Study): Pilot Randomized Controlled Trial.Journal of medical Internet research · 2018Trial
- Community-based group guided self-help intervention for low mood and stress: randomised controlled trial.The British journal of psychiatry : the journal of mental science · 2018Trial
- Online CBT life skills programme for low mood and anxiety: study protocol for a pilot randomized controlled trial.Trials · 2016Trial
- A community-based pilot randomised controlled study of life skills classes for individuals with low mood and depression.BMC psychiatry · 2015Trial
- Trial
- Trial
- The Digital Therapeutic Alliance With Mental Health Chatbots: Diary Study and Thematic Analysis.JMIR mental health · 2025Article
- Article
- Online Cognitive Behavioral Therapy (CBT) Life Skills Program for Depression: Pilot Randomized Controlled Trial.JMIR formative research · 2022Article
- Digital Health Needs of Women With Postpartum Depression: Focus Group Study.Journal of medical Internet research · 2021Article
- Article
- Bibliotherapy: Reading OVID During COVID.Frontiers in psychiatry · 2020Article
- Barriers to Behavioral Treatment Adherence for Headache: An Examination of Attitudes, Beliefs, and Psychiatric Factors.Headache · 2019Review
- Addressing Behavioral Health Disparities for Somali Immigrants Through Group Cognitive Behavioral Therapy Led by Community Health Workers.Journal of immigrant and minority health · 2017Article
- How effective are cognitive behavior therapies for major depression and anxiety disorders? A meta-analytic update of the evidence.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2016Article
- Behavioural activation written self-help to improve mood, wellbeing and quality of life in people with dementia supported by informal carers (PROMOTE): a study protocol for a single-arm feasibility study.Pilot and feasibility studies · 2016Article
Corrections and comments
- Erratum issuedAndrew, Walker [corrected to Walker, Andrew]
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAccess to Cognitive behavioural therapy (CBT) for depression is limited. One solution is CBT self-help books. Trial Objectives: To assess the impact of a guided self-help CBT book (GSH-CBT) on mood, compared to treatment as usual (TAU). HYPOTHESES: GSH-CBT will have improved mood and knowledge of the causes and treatment of depression compared to the control receiving TAUGuided self-help will be acceptable to patients and staff. METHODS AND
findings
participantsAdults attending seven general practices in Glasgow, UK with a BDI-II score of ≥14. 141 randomised to GSH-CBT and 140 to TAU.
interventionsRCT comparing 'Overcoming Depression: A Five Areas Approach' book plus 3-4 short face to face support appointments totalling up to 2 hours of guided support, compared with general practitioner TAU. PRIMARY OUTCOME: The BDI (II) score at 4 months. Numbers analysed: 281 at baseline, 203 at 4 months (primary outcome), 117 at 12 months. OUTCOME: Mean BDI-II scores were lower in the GSH-CBT group at 4 months by 5.3 points (2.6 to 7.9, p<0.001). At 4 and 12 months there were also significantly higher proportions of participants achieving a 50% reduction in BDI-II in the GSH-CBT arm. The mean support was 2 sessions with 42.7 minutes for session 1, 41.4 minutes for session 2 and 40.2 minutes of support for session 3. Adverse effects/Harms: Significantly less deterioration in mood in GSH-CBT (2.0% compared to 9.8% in the TAU group for BDI-II category change). LIMITATIONS: Weaknesses: Our follow-up rate of 72.2% at 4 months is better than predicted but is poorer at 12 months (41.6%). In the GSH-CBT arm, around 50% of people attended 2 or fewer sessions. 22% failed to take up treatment.
conclusionsGSH-CBT is substantially more effective than TAU.
trial registrationControlled-Trials.com ISRCTN13475030.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.