ArticleLaboratory animal research2012
Analysis of reference interval and age-related changes in serum biochemistry and hematology in the specific pathogen free miniature pig.
Article in Laboratory animal research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
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- Hematological reference intervals for Danish crossbred Landrace Yorkshire Duroc (LYD) pigs used in biomedical research.Acta veterinaria Scandinavica · 2025Article
- Analysis of growth rate, haematologic, and biochemical parameters of Oncopigs.International journal of veterinary science and medicine · 2025Article
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- Preliminary research on tailored fluid therapy in pigs: comparing customized ionic solutions with Hartmann's solution.BMC veterinary research · 2024Article
- Analysis of blood composition by porcine breeding cycle.Veterinary medicine and science · 2024Article
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- Safety assessment of a three-dimensional-printed autologous omentum patch: An application on the kidneys as a new treatment approach.Clinical and translational science · 2023Article
- Haematological reference intervals of sows at end gestation in ten French herds, the impact of parity on haematological parameters and the consequences on reproductive performance.Porcine health management · 2021Article
- A new minimally invasive porcine model for the study of intrahepatic bile duct dilatation.Surgical endoscopy · 2021Article
- Biochemistry and Immune Biomarkers Indicate Interacting Effects of Pre- and Postnatal Stressors in Pigs across Sexes.Animals : an open access journal from MDPI · 2021Article
- Early Metabolic and Inflammatory Intraperitoneal Changes After Rectum Perforation.Annals of coloproctology · 2020Article
- Leukocyte populations and their cell adhesion molecules expression in newborn dromedary camel calves.Veterinary world · 2020Article
- Comparison of hematologic and biochemical reference values in specific-pathogen-free 1-month-old Yorkshire pigs and Yorkshire-Landrace crossbred pigs.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2019Article
- Porcine Breed, Sex, and Production Stage Influence the Levels of Health Status Biomarkers in Saliva Samples.Frontiers in veterinary science · 2019Article
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Authors and funding
4 authors.
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Abstract
We analyzed 72 items related to serum biochemistry and hematology in 85 specific pathogen-free (SPF) Seoul National University (SNU) miniature pigs aged 1- to 36-months which originated from a Minnesota miniature pig. Almost all examined items were similar between male and female pigs. However, some items such as Cr level, B/C ratio, C.R.F, LDH, LAP and T4 were significantly different between male and female pigs (P<0.05). Thirty four examined items showed age-related changes, and the significant changes were observed in animals less than six months old. The values for BUN, K, uric acid, Ca, Ca(++), and Pi were significantly higher in pigs younger than six months of age, which might reflect poor kidney function in young pigs. Additionally, TIBC, UIBC and RDW were significantly higher in young pigs, and RBC, Hb, HCT, MCHC and MCV were significantly lower in young pigs, thus indicating a similar physiology of iron deficiency anemia. These age-related specific phenotypes seemed to be normal, but it should be considered in the long-term experiment using the young pigs. In conclusion, in this study, we defined the normal reference intervals for SPF SNU miniature pigs, and we also determined that there are some physiological differences between the pig genders and ages. This study provides fundamental data for use in experiments involving SPF SNU miniature pigs.
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