Evidence map›Paper›PMID 23326202›Full record

ArticleClinical, cosmetic and investigational dermatology2013

Characterization and evolution of dermal filaments from patients with Morgellons disease.

Marianne J Middelveen, Peter J Mayne, Douglas G Kahn, Raphael B Stricker

Open access · goldAbstract read
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Article
  3. Dermatological and Genital Manifestations of Lyme Disease Including Morgellons Disease.Clinical, cosmetic and investigational dermatology · 2021
    Article
  4. Classification and Staging of Morgellons Disease: Lessons from Syphilis.Clinical, cosmetic and investigational dermatology · 2020
    Article
  5. MixedHealthcare (Basel, Switzerland) · 2019
    Article
  6. Article
  7. History of Morgellons disease: from delusion to definition.Clinical, cosmetic and investigational dermatology · 2018
    Review
  8. Article
  9. Morgellons Disease.Annals of dermatology · 2017
    Article
  10. Morgellons disease: a filamentous borrelial dermatitis.International journal of general medicine · 2016
    Review
  11. Article
  12. Article
  13. Culture and identification ofF1000Research · 2014
    Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Marianne J MiddelveenInternational Lyme and Associated Diseases Society, Bethesda, MD, USA;
Peter J Mayne
Douglas G Kahn
Raphael B Stricker
Infectious Diseases Society of America · USInternational Lyme and Associated Diseases SocietyOlive View-UCLA Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Morgellons disease is an emerging skin disease characterized by formation of dermal filaments associated with multisystemic symptoms and tick-borne illness. Some clinicians hypothesize that these often colorful dermal filaments are textile fibers, either self-implanted by patients or accidentally adhering to lesions, and conclude that patients with this disease have delusions of infestation. We present histological observations and electron microscopic imaging from representative Morgellons disease samples revealing that dermal filaments in these cases are keratin and collagen in composition and result from proliferation and activation of keratinocytes and fibroblasts in the epidermis. Spirochetes were detected in the dermatological specimens from our study patients, providing evidence that Morgellons disease is associated with an infectious process.

Indexed as

Borrelia burgdorfericollagendigital dermatitisfibroblastskeratinkeratinocytesLyme diseaseMorgellons diseasespirochetes

Identifiers

PMID23326202
PMCPMC3544355
OpenAlexW1981739113

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.