Evidence map›Paper›PMID 23325549›Full record

ArticleMedical molecular morphology2013

The effect of cinnamaldehyde on the growth and the morphology of Candida albicans.

Yuuki Taguchi, Yayoi Hasumi, Shigeru Abe, Yayoi Nishiyama

Abstract read
PubMed Publisher
In one paragraph

Article in Medical molecular morphology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Antimicrobial Effect of Cinnamaldehyde andInternational journal of microbiology · 2025
    Article
  5. Pharmaceutics · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Fungal biology and biotechnology · 2018
    Article
  17. The first case of onychomycosis in a koala (Current medical mycology · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yuuki TaguchiResearch and Product Development Division, S&B Foods Inc., 38-8 Miyamoto-cho, Itabashiku, Tokyo, Japan. yuuki_taguchi@sbfoods.co.jp
Yayoi Hasumi
Shigeru Abe
Yayoi Nishiyama
Teikyo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We examined the viability and morphology of Candida albicans under experimental conditions after treatment with varying concentrations of cinnamaldehyde, the major component of cassia (Cinnamomum cassia), using XTT assay, fluorescent microscopy, scanning electron microscopy, and thin-section electron microscopy. At 10 μg/ml level, cinnamaldehyde inhibited mycelial growth, but did not affect the growth of yeast cells, metabolic activity, cell shape, or the ultrastructure of the cells. At 40 μg/ml level, cinnamaldehyde showed fungicidal activity accompanied by alteration of the membrane and interior of Candida cells. These findings indicate that cinnamaldehyde has both fungistatic and fungicidal activities against C. albicans and affects the structure of the cells.

Indexed as

AcroleinCandida albicansCell MembraneCinnamomum aromaticumDose-Response Relationship, DrugMicroscopy, Electron, ScanningMicroscopy, FluorescenceMicrotomyMyceliumTetrazolium Salts2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-5-((phenylamino)carbonyl)-2H-tetrazolium hydroxideAcroleincinnamaldehydeTetrazolium Salts

Identifiers

PMID23325549
OpenAlexW1979473231

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.