ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2013
Salience signals in the right temporoparietal junction facilitate value-based decisions.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
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Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it.
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- Neural Representation of Valenced and Generic Probability and Uncertainty.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
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- Behavioral and fMRI evidence that arousal enhances bottom-up selectivity in young but not older adults.Neurobiology of aging · 2022Article
- Dynamic computation of value signals via a common neural network in multi-attribute decision-making.Social cognitive and affective neuroscience · 2022Article
- Mapping the effects of atomoxetine during response inhibition across cortical territories and the locus coeruleus.Psychopharmacology · 2022Article
- Computational and Neurobiological Substrates of Cost-Benefit Integration in Altruistic Helping Decision.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
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- Sex Differences and Commonalities in the Impact of a Palatable Meal on Thalamic and Insular Connectivity.Nutrients · 2020Article
- Noradrenergic-dependent functions are associated with age-related locus coeruleus signal intensity differences.Nature communications · 2020Article
- Electrophysiological and Behavioral Correlates of Valence, Arousal and Subjective Significance in the Lexical Decision Task.Frontiers in human neuroscience · 2020Article
- The Role of Social Reward and Corticostriatal Connectivity in Substance Use.Journal of psychiatry and brain science · 2020Article
- Luring the Motor System: Impact of Performance-Contingent Incentives on Pre-Movement Beta-Band Activity and Motor Performance.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Attentional capture by simultaneous pleasant and unpleasant emotional distractors.Emotion (Washington, D.C.) · 2018Article
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2 authors.
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Abstract
Value-based decisions optimize the relation of costs and benefits. Costs and benefits confer not only value but also salience, which may influence decision making through attentional mechanisms. However, the computational and neurobiological role of salience in value-based decisions remains elusive. Here we develop and contrast two formal concepts of salience for value-based choices involving costs and benefits. Specifically, global salience (GS) first integrates costs and benefits and then determines salience based on this overall sum, whereas elemental salience (ES) first determines the salience of costs and benefits before integrating them. We dissociate the behavioral and neural effects of GS and ES from those of value using a value-based decision-making task and fMRI in humans. Specifically, we show that value guides choices and correlates with neural signals in the striatum. In contrast, only ES but not GS impacts decision making by speeding up reaction times. Moreover, activity in the right temporoparietal junction (RTPJ) reflects only ES and correlates with its response-accelerating behavioral effects. Finally, we report an ES-dependent change in functional connectivity between the RTPJ and the locus ceruleus, suggesting noradrenergic processes underlying the response-facilitating effects of ES on decision making. Together, these results support a novel concept of salience in value-based decision making and suggest a computational, anatomical, and neurochemical dissociation of value- and salience-based factors supporting value-based choices.
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