ArticleThe Journal of investigative dermatology2013
Dependence of deodorant usage on ABCC11 genotype: scope for personalized genetics in personal hygiene.
Article in The Journal of investigative dermatology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 23 citations in OpenAlex.
- Genomic profiling of a six-generation patrilineal family of the Ming-Qing dynasties in China.iScience · 2025Article
- Personal care product use among diverse women in California: Taking Stock Study.Journal of exposure science & environmental epidemiology · 2021Article
- Data Resource Profile: The ALSPAC birth cohort as a platform to study the relationship of environment and health and social factors.International journal of epidemiology · 2019Article
- A missense variant of the ABCC11 gene is associated with Axillary Osmidrosis susceptibility and clinical phenotypes in the Chinese Han Population.Scientific reports · 2017Article
- Characterising private and shared signatures of positive selection in 37 Asian populations.European journal of human genetics : EJHG · 2017Article
- Clinical and Molecular Evidence of ABCC11 Protein Expression in Axillary Apocrine Glands of Patients with Axillary Osmidrosis.International journal of molecular sciences · 2017Article
- Genome-wide data from two early Neolithic East Asian individuals dating to 7700 years ago.Science advances · 2017Article
- Diagnosis of Human Axillary Osmidrosis by Genotyping of the Human ABCC11 Gene: Clinical Practice and Basic Scientific Evidence.BioMed research international · 2016Review
- Effect of fragrance use on discrimination of individual body odor.Frontiers in psychology · 2015Article
- Personality, behavior and environmental features associated with OXTR genetic variants in British mothers.PloS one · 2014Article
- [What's new in clinical dermatology?].Annales de dermatologie et de venereologie · 2013Review
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Earwax type and axillary odor are genetically determined by rs17822931, a single-nucleotide polymorphism (SNP) located in the ABCC11 gene. The literature has been concerned with the Mendelian trait of earwax, although axillary odor is also Mendelian. Ethnic diversity in rs17822931 exists, with higher frequency of allele A in east Asians. Influence on deodorant usage has not been investigated. In this work, we present a detailed analysis of the rs17822931 effect on deodorant usage in a large (N∼17,000 individuals) population cohort (the Avon Longitudinal Study of Parents and Children (ALSPAC)). We found strong evidence (P=3.7 × 10(-20)) indicating differential deodorant usage according to the rs17822931 genotype. AA homozygotes were almost 5-fold overrepresented in categories of never using deodorant or using it infrequently. However, 77.8% of white European genotypically nonodorous individuals still used deodorant, and 4.7% genotypically odorous individuals did not. We provide evidence of a behavioral effect associated with rs17822931. This effect has a biological basis that can result in a change in the family's environment if an aerosol deodorant is used. It also indicates potential cost saving to the nonodorous and scope for personalized genetics usage in personal hygiene choices, with consequent reduction of inappropriate chemical exposures for some.
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