Evidence map›Paper›PMID 23324557›Full record

Trial reportBMC medical imaging2013

Radiofrequency ablation of liver tumors: quantitative assessment of tumor coverage through CT image processing.

Katia Passera, Sabrina Selvaggi, Davide Scaramuzza, Francesco Garbagnati, Daniele Vergnaghi, Luca Mainardi

Open access · goldAbstract readClinical TrialValidation Study
In one paragraph

Trial report in BMC medical imaging, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Multimodality liver registration of Open-MR and CT scans.International journal of computer assisted radiology and surgery · 2015
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Katia PasseraIstituto di Ricerche Farmacologiche Mario Negri – IRCCS, Bergamo, Italy.
Sabrina Selvaggi
Davide Scaramuzza
Francesco Garbagnati
Daniele Vergnaghi
Luca Mainardi
Fondazione IRCCS Istituto Nazionale dei Tumori · ITPolitecnico di Milano · ITMario Negri Institute for Pharmacological Research · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRadiofrequency ablation (RFA) is one of the most promising non-surgical treatments for hepatic tumors. The assessment of the therapeutic efficacy of RFA is usually obtained by visual comparison of pre- and post-treatment CT images, but no numerical quantification is performed.

methodsIn this work, a novel method aiming at providing a more objective tool for the evaluation of RFA coverage is described. Image registration and segmentation techniques were applied to enable the visualization of the tumor and the corresponding post-RFA necrosis in the same framework. In addition, a set of numerical indexes describing tumor/necrosis overlap and their mutual position were computed.

resultsAfter validation of segmentation step, the method was applied on a dataset composed by 10 tumors, suspected not to be completed treated. Numerical indexes showed that only two tumors were totally treated and the percentage of a residual tumor was in the range of 5.12%-35.92%.

conclusionsThis work represents a first attempt to obtain a quantitative tool aimed to assess the accuracy of RFA treatment. The possibility to visualize the tumor and the correspondent post-RFA necrosis in the same framework and the definition of some synthetic numerical indexes could help clinicians in ameliorating RFA treatment.

Indexed as

AdultAgedAged, 80 and overAlgorithmsCatheter AblationHumansImaging, Three-DimensionalLiver NeoplasmsMaleMiddle AgedPattern Recognition, AutomatedRadiographic Image EnhancementRadiographic Image Interpretation, Computer-AssistedReproducibility of ResultsSensitivity and SpecificitySurgery, Computer-Assisted

Identifiers

PMID23324557
PMCPMC3626768
OpenAlexW2040797241

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.