Evidence map›Paper›PMID 23324218›Full record

ArticleThe American journal of tropical medicine and hygiene2013

Leishmania major, the predominant Leishmania species responsible for cutaneous leishmaniasis in Mali.

Carlos Paz, Sibiry Samake, Jennifer M Anderson, Ousmane Faye, Pierre Traore, Koureishi Tall, Moumine Cisse, Somita Keita, Jesus G Valenzuela, Seydou Doumbia

Registry-linked trialAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06692985 (Sentinel Surveillance of Cutaneous Leishmaniasis in Sub-Saharan Africa Based on Non-invasive Molecular Diagnostics), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06692985 completednot on this mapstarted 2023, after this paper: background citation

Sentinel Surveillance of Cutaneous Leishmaniasis in Sub-Saharan Africa Based on Non-invasive Molecular Diagnostics: Mapping of Human Cases, Description of Leishamania Species Involved

TypeobservationalSponsorCentre Hospitalier de CayenneRan2023 to 2024Enrolled270ConditionsCutaneous LeishmaniasisArmsClinical and epidemiological data, Parasitological samples, Assessment of clinical course and response to treatment, DLQI questionnaire
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. NanoformulatedNanomaterials (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Carlos PazSection of Dermatology, University of Chicago, Chicago, IL, USA. Carlos.Paz@uchospitals.edu
Sibiry Samake
Jennifer M Anderson
Ousmane Faye
Pierre Traore
Koureishi Tall
Moumine Cisse
Somita Keita
Jesus G Valenzuela
Seydou Doumbia

Funding

Molecular approaches to understand vector-host and vector-pathogen interactionsZIAAI000932 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI VALENZUELA, JESUS · 2009 to 2025
$23.1M
Intramural NIH HHS
6 · The paper itself

Abstract

Leishmania major is the only species of Leishmania known to cause cutaneous leishmanisis (CL) in Mali. We amplified Leishmania DNA stored on archived Giemsa-stained dermal scraping slides obtained from self-referral patients with clinically suspected CL seen in the Center National d'Appui A La Lutte Contre La Maladie (CNAM) in Bamako, Mali, to determine if any other Leishmania species were responsible for CL in Mali and evaluate its geographic distribution. Polymerase chain reaction (PCR) amplification was performed using a Leishmania species-specific primer pair that can amplify DNA from L. major, L. tropica, L. infantum, and L. donovani parasites, possible causative agents of CL in Mali. L. major was the only species detected in 41 microscopically confirmed cases of CL from five regions of Mali (Kayes, Koulikoro, Ségou, Mopti, and Tombouctou). These results implicate L. major as the predominant, possibly exclusive species responsible for CL in Mali.

Indexed as

DNA, KinetoplastDNA, ProtozoanHumansLeishmania majorLeishmaniasis, CutaneousMaliPolymerase Chain ReactionPopulation SurveillanceSensitivity and SpecificitySkinSpecies SpecificityDNA, KinetoplastDNA, Protozoan

Identifiers

PMID23324218
PMCPMC3592546

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.